Department of Clinical Laboratory,The Second Affiliated Hospital of Nanchang University, Jiangxi Province Key Laboratory of Laboratory Medicine, Nanchang 330006, Jiangxi, China.
Department of Clinical Laboratory,The Second Affiliated Hospital of Nanchang University, Jiangxi Province Key Laboratory of Laboratory Medicine, Nanchang 330006, Jiangxi, China.
Clin Chim Acta. 2018 Jul;482:172-177. doi: 10.1016/j.cca.2018.03.042. Epub 2018 Mar 31.
Dermatomyositis (DM) and polymyositis (PM) are heterogeneous complex autoimmune diseases involving muscle damage. Patients with DM and PM display a wide spectrum of clinical manifestations and serological biomarkers, which may mislead and delay the proper diagnosis. Therefore, specific biomarkers or indicators for diagnosing DM and PM and monitoring disease activity are essential. Significant progress has been made through identifying novel serological biomarkers for DM and PM in recent years. Our aim is to focus on novel biomarkers for diagnosing and monitoring disease activity in DM and PM to highlight their predictive value and applicability in clinical practice.
皮肌炎（DM）和多发性肌炎（PM）是涉及肌肉损伤的异质性复杂自身免疫性疾病。DM 和 PM 患者表现出广泛的临床表现和血清生物标志物，这可能会导致误诊和延误正确诊断。因此，用于诊断 DM 和 PM 以及监测疾病活动的特定生物标志物或指标是必不可少的。近年来，通过鉴定 DM 和 PM 的新型血清生物标志物，取得了重大进展。我们的目的是重点关注 DM 和 PM 中用于诊断和监测疾病活动的新型生物标志物，以突出它们在临床实践中的预测价值和适用性。
