McEniery P T, Hollman J, Knezinek V, Dorosti K, Franco I, Simpfendorfer C, Whitlow P
Cleveland Clinic Foundation, OH 44106.
Cathet Cardiovasc Diagn. 1987 Nov-Dec;13(6):364-71. doi: 10.1002/ccd.1810130602.
In early reports of percutaneous transluminal coronary angioplasty (PTCA) in women, the complication rate was higher and the success rate lower than in men. From December, 1980, to December, 1986, 969 women aged 61 (32-84) years and 2,727 men aged 57 (27-84) years underwent PTCA, at our institution. At the time of PTCA 26% of the women had functional class IV angina pectoris compared to 16% of the men (P less than 0.005). Women more often had hypertension (56% vs 39%), left ventricular hypertrophy, diabetes mellitus (19% vs 11%; P less than 0.0005), and family history of coronary artery disease than men. Significantly more of the men (74%) smoked than did the women (53%). The success rate in women was 93% as compared to an angiographic success rate in 2,727 men of 93.5% (ns). The rate of emergency bypass surgery in women was 3.8% as compared to 3.2% in men (ns). The death rate was 0.3% in women as compared to 0.09% in men. Women underwent more PTCA of the left anterior descending coronary artery (52% vs 48% of lesions in men; P less than 0.05) and right coronary artery (32% vs 27% in men; P less than 0.0005). Fewer of the women (9%) had had previous bypass surgery than had the men (15% P less than 0.0005). Procedural details, including balloon diameter, vessel diameter, lesion response pressure, inflation number, and maximum inflation pressures used as PTCA, were not different between men and women. Women had significantly more ST segment shift of 1 mm of more at the time of balloon inflation than men (P less than 0.0005).(ABSTRACT TRUNCATED AT 250 WORDS)
在关于女性经皮腔内冠状动脉成形术（PTCA）的早期报告中，其并发症发生率高于男性，成功率低于男性。1980年12月至1986年12月，在我们机构，969名年龄为61岁（32 - 84岁）的女性和2727名年龄为57岁（27 - 84岁）的男性接受了PTCA。在进行PTCA时，26%的女性有IV级心绞痛功能分级，而男性为16%（P < 0.005）。女性比男性更常患有高血压（56%对39%）、左心室肥厚、糖尿病（19%对11%；P < 0.0005）以及有冠状动脉疾病家族史。吸烟的男性（74%）明显多于女性（53%）。女性的成功率为93%，而2727名男性的血管造影成功率为93.5%（无显著差异）。女性急诊搭桥手术率为3.8%，男性为3.2%（无显著差异）。女性死亡率为0.3%，男性为0.09%。女性接受左前降支冠状动脉PTCA的比例更高（52%对男性病变的48%；P < 0.05），右冠状动脉PTCA的比例也更高（32%对男性的27%；P < 0.0005）。接受过搭桥手术的女性（9%）少于男性（15%，P < 0.0005）。PTCA的操作细节，包括球囊直径、血管直径、病变反应压力、充盈次数以及使用的最大充盈压力，男女之间并无差异。女性在球囊充盈时ST段移位≥1mm的情况明显多于男性（P < 0.0005）。（摘要截断于250字）
