Li Yanhong, Li Yan, Zhang Xian, Zhao Lin, Chen Liqin, Sun Haisong
1 Department of Pediatrics, The Second Affiliated Hospital of Kunming Medical University, Kunming, Yunnan Province, China.
2 School of Public Health, Kunming Medical University, Kunming, Yunnan Province, China.
Food Nutr Bull. 2018 Jun;39(2):260-265. doi: 10.1177/0379572118765825. Epub 2018 Apr 3.
To determine the prevalence of vitamin D deficiency in 6- to 23-month-old children from 4 different ethnic groups, Han, Lisu, Hani, and Bai, in Yunnan Province of China.
A large cohort of 938 young children aged 6 to 23 months who were living in Yunnan, China (23°28'-27°52' N), were selected and recruited in this study. Venous-blood sampling was conducted in all the participants, and serum 25-hydroxyvitamin D [25(OH)D] levels were measured. The children's physical status was measured.
General mean serum 25(OH)D level was 21.46 ± 7.95 ng/mL, which was obtained from a total of 938 cases. No significant difference was found in age, gender, height, and weight of participants from different ethnic groups. The mean 25(OH)D level was significantly lower in children of Lisu ethnic groups compared with that of Han and Hani participants, respectively ( P < .05). In addition, Bai children had lower 25(OH)D content than Hani children ( P < .001). Among the children with 25(OH)D sufficiency, the number of Lisu participants was significantly lower than Han children ( P < .001).
The prevalence of vitamin D deficiency varied among the ethnically different children in Yunnan, China, and significantly fewer Lisu children maintained vitamin D sufficiency compared with other ethnic children. Recognizing these ethnic differences in treating children with vitamin D deficiency may improve the therapeutic outcome.
确定中国云南省汉族、傈僳族、哈尼族和白族4个不同民族6至23个月大儿童维生素D缺乏症的患病率。
本研究选取并招募了938名居住在中国云南（北纬23°28′-27°52′）的6至23个月大的幼儿。对所有参与者进行静脉血采样，并测量血清25-羟基维生素D[25(OH)D]水平。测量儿童的身体状况。
共938例样本的血清25(OH)D总体平均水平为21.46±7.95 ng/mL。不同民族参与者的年龄、性别、身高和体重未发现显著差异。傈僳族儿童的平均25(OH)D水平分别显著低于汉族和哈尼族参与者（P<.05）。此外，白族儿童的25(OH)D含量低于哈尼族儿童（P<.001）。在25(OH)D充足的儿童中，傈僳族参与者的数量显著低于汉族儿童（P<.001）。
中国云南不同民族儿童维生素D缺乏症的患病率存在差异，与其他民族儿童相比，傈僳族儿童维持维生素D充足的人数明显较少。认识到这些民族差异可能会改善维生素D缺乏症儿童的治疗效果。
