Lu J X, Liu X B, Chen J, Hu Y C, Yun C F, Li W D, Wang R, Yang Y H, Mao D Q, Piao J H, Yang X G, Yang L C
National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention; Key Laboratory of Trace Element Nutrition, National Health and Family Planning Commission, Beijing 100050, China.
Zhonghua Yu Fang Yi Xue Za Zhi. 2017 Feb 6;51(2):112-116. doi: 10.3760/cma.j.issn.0253-9624.2017.02.003.
To evaluate the vitamin D nutritional status in Chinese women of child-bearing age by analyzing serum 25-hydroxyvitamin D level in 2010-2012. Data were obtained from the China Nutrition and Health Survey in 2010-2012. Using cluster sampling and proportional stratified random sampling, 1 514 women of child-bearing age (18-44 years old) from 34 metropolis and 41 small and medium-sized cities were included in this study. Demographic information was collected by questionnaire and serum 25-hydroxyvitamin D concentration was determined by radioimmunoassay, in accordance with the 2010 Institute of Medicine of the National Academies standards. We compared differences in vitamin D levels, specifically serious deficiency, lack of deficiency, insufficiency, and excess. The overall serum 25-hydroxyvitamin D level of Chinese urban women of child-bearing age ((50) ((25)-(75))) was 20.1 (15.1-26.3) ng/ml; minorities had a significantly higher serum 25-hydroxyvitamin D level of 22.0 (15.9-27.5) ng/ml compared with women of Han nationality (19.8 (14.9-26.2) ng/ml) (χ(2)=7.02, 0.008). The proportions of women with serious deficiency, lack of deficiency, insufficiency, and excess vitamin D were 11.6% (175), 37.9% (574), 35.1% (531), and 0.3% (5), respectively. Only 15.1% (229) of women of child-bearing age had normal vitamin D nutritional status. No significant differences in vitamin D nutritional status were observed according to age, body mass index, city, nationality, educational level, marital status, or household income per capita (0.05). Most Chinese urban women of child-bearing age have poor vitamin D levels and require vitamin D supplementation.
通过分析2010 - 2012年血清25 - 羟基维生素D水平来评估中国育龄妇女的维生素D营养状况。数据来自2010 - 2012年中国营养与健康调查。采用整群抽样和按比例分层随机抽样，本研究纳入了来自34个大城市和41个中小城市的1514名育龄妇女（18 - 44岁）。通过问卷调查收集人口统计学信息，并根据2010年美国国家科学院医学研究所的标准，采用放射免疫分析法测定血清25 - 羟基维生素D浓度。我们比较了维生素D水平的差异，特别是严重缺乏、缺乏、不足和过量的差异。中国城市育龄妇女的血清25 - 羟基维生素D总体水平（（50）（（25） - （75）））为20.1（15.1 - 26.3）ng/ml；少数民族血清25 - 羟基维生素D水平显著高于汉族妇女，分别为22.0（15.9 - 27.5）ng/ml和19.8（14.9 - 26.2）ng/ml（χ（2） = 7.02，P = 0.008）。维生素D严重缺乏、缺乏、不足和过量的妇女比例分别为11.6%（175人）、37.9%（574人）、35.1%（531人）和0.3%（5人）。只有15.1%（229人）的育龄妇女维生素D营养状况正常。根据年龄、体重指数、城市、民族、教育程度、婚姻状况或人均家庭收入，未观察到维生素D营养状况的显著差异（P＞0.05）。大多数中国城市育龄妇女维生素D水平较差，需要补充维生素D。
