The Zena and Michael A. Wiener Cardiovascular Institute and Cardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Trends Endocrinol Metab. 2018 Aug;29(8):527-529. doi: 10.1016/j.tem.2018.03.015. Epub 2018 Mar 31.
Endothelial to mesenchymal transition (EndMT) involves cellular phenotypic switching from an endothelial to mesenchymal state. Interest in EndMT has been increasing with the appreciation that it has an important role in several cardiovascular diseases. New evidence indicates that fatty acid oxidation (FAO) and cell metabolism are major factors controlling this process.
内皮细胞向间充质细胞转化（EndMT）涉及细胞表型从内皮状态向间充质状态的转变。随着人们认识到它在几种心血管疾病中起着重要作用，对 EndMT 的兴趣日益增加。新的证据表明，脂肪酸氧化（FAO）和细胞代谢是控制这一过程的主要因素。
