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用旋转血栓弹力图诊断犬急性创伤性凝血病中的高纤维蛋白溶解,并使用氨甲环酸进行治疗。

Hyperfibrinolysis diagnosed with rotational thromboelastometry and treated with tranexamic acid in a dog with acute traumatic coagulopathy.

作者信息

Muri B, Schmierer P, Schwarz A, Sigrist N

机构信息

Department for Small Animals, Vetsuisse Faculty, University of Zurich.

Clinic for Small Animal Surgery, Vetsuisse Faculty, University of Zurich.

出版信息

Schweiz Arch Tierheilkd. 2018 Apr;160(4):227-233. doi: 10.17236/sat00155.

DOI:10.17236/sat00155
PMID:29615381
Abstract

A 4-year old male Australian Cattle Dog involved in a road traffic accident was presented with severe polytrauma to the Small Animal Clinic, University of Zurich. He was presented in hemorrhagic shock, with an initial lactate of 10.3mmol/l and ongoing bleeding from multiple injury sites. Acute traumatic coagulopathy diagnosed with ROTEM within one hour after accident showed marked hypocoagulation and hyperfibrinolysis. Treatment with a total dose of 40mg/kg of tranexamic acid intravenously resulted in successful elimination of hyperfibrinolysis in the following, serially measured ROTEM tracings.

摘要

一只4岁雄性澳大利亚牧牛犬遭遇道路交通事故后,被送至苏黎世大学小动物诊所,呈现出严重的多发伤。它因失血性休克就诊,初始乳酸水平为10.3mmol/l,且多个损伤部位持续出血。事故发生后一小时内通过旋转血栓弹力图(ROTEM)诊断出急性创伤性凝血病,显示出明显的低凝和高纤维蛋白溶解。静脉注射总量为40mg/kg的氨甲环酸进行治疗,在随后连续测量的ROTEM描记图中成功消除了高纤维蛋白溶解。

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