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从战场汲取的经验教训及其在兽医学中的适用性——第1部分:出血控制

Lessons Learned From the Battlefield and Applicability to Veterinary Medicine-Part 1: Hemorrhage Control.

作者信息

Edwards Thomas H, Dubick Michael A, Palmer Lee, Pusateri Anthony E

机构信息

US Army Institute of Surgical Research, Joint Base San Antonio, San Antonio, TX, United States.

Special Forces Group, Alabama Army National Guard, Auburn, AL, United States.

出版信息

Front Vet Sci. 2021 Jan 14;7:571368. doi: 10.3389/fvets.2020.571368. eCollection 2020.

Abstract

In humans, the leading cause of potentially preventable death on the modern battlefield is undoubtedly exsanguination from massive hemorrhage. The US military and allied nations have devoted enormous effort to combat hemorrhagic shock and massive hemorrhage. This has yielded numerous advances designed to stop bleeding and save lives. The development of extremity, junctional and truncal tourniquets applied by first responders have saved countless lives both on the battlefield and in civilian settings. Additional devices such as resuscitative endovascular balloon occlusion of the aorta (REBOA) and intraperitoneal hemostatic foams show great promise to address control the most difficult forms (non-compressible) of hemorrhage. The development of next generation hemostatic dressings has reduced bleeding both in the prehospital setting as well as in the operating room. Furthermore, the research and fielding of antifibrinolytics such as tranexamic acid have shown incredible promise to ameliorate the effects of acute traumatic coagulopathy which has led to significant morbidity and mortality in service members. Advances from lessons learned on the battlefield have numerous potential parallels in veterinary medicine and these lessons are ripe for translation to veterinary medicine.

摘要

在人类中,现代战场上潜在可预防死亡的主要原因无疑是大量出血导致的失血过多。美国军方和盟友国家投入了巨大努力来对抗失血性休克和大量出血。这带来了许多旨在止血和挽救生命的进展。急救人员使用的四肢、关节和躯干止血带的发展,在战场和民用环境中都挽救了无数生命。其他设备,如主动脉内复苏球囊阻塞术(REBOA)和腹腔内止血泡沫,在控制最困难的出血形式(不可压缩性出血)方面显示出巨大潜力。下一代止血敷料的研发减少了院前和手术室的出血情况。此外,氨甲环酸等抗纤溶药物的研究和应用,在改善急性创伤性凝血病的影响方面显示出了惊人的前景,急性创伤性凝血病已导致军人出现显著的发病率和死亡率。从战场上吸取的经验教训在兽医学中有许多潜在的相似之处,这些经验教训已成熟到可以转化应用于兽医学。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/350d/7841008/95c512644ce5/fvets-07-571368-g0001.jpg

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