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急诊科出院的高血压患者的医生随访及循证药物的长期使用:一项前瞻性队列研究。

Physician follow-up and long-term use of evidence-based medication for patients with hypertension who were discharged from an emergency department: a prospective cohort study.

作者信息

Atzema Clare L, Yu Bing, Schull Michael J, Jackevicius Cynthia A, Ivers Noah M, Lee Douglas S, Rochon Paula, Austin Peter C

机构信息

Affiliations: Institute for Clinical Evaluative Sciences (Atzema, Yu, Schull, Jackevicius, Ivers, Lee, Rochon, Austin), Toronto, Ont.; Division of Emergency Medicine (Atzema, Schull) and Cardiology (Lee), the Department of Medicine, Department of Family and Community Medicine (Ivers), and the Institute for Health Policy, Management and Evaluation (Atzema, Schull, Jackevicius, Ivers, Lee, Rochon, Austin), University of Toronto, Toronto, Ont.; Sunnybrook Health Sciences Centre (Atzema, Schull, Tu, Austin), Women's College Hospital (Ivers, Rochon), University Health Network (Jackevicius, Lee), Toronto, Ont.; Western University of Health Sciences, Pomona, Calif., and the Veteran's Affairs Greater Los Angeles Healthcare System (Jackevicius), Los Angeles, Calif.

出版信息

CMAJ Open. 2018 Apr 3;6(2):E151-E161. doi: 10.9778/cmajo.20170119.

Abstract

BACKGROUND

More than 25% of the population has hypertension. The number of patients seeking care for hypertension in emergency departments has increased by more than 60% in the last decade, with less than 10% of these patients subsequently admitted to hospital. Managing physicians recommend early follow-up to patients who are discharged from the emergency department, but there is a paucity of literature assessing the impact or timing of follow-up on patient outcomes.

METHODS

Using a population-based cohort design, we included patients more than 65 years of age who were discharged from an Ontario emergency department with a primary diagnosis of hypertension between 2007 and 2014. We identified 2 cohorts: an incident cohort, and a cohort in which patients were on no more than 1 class of evidence-based antihypertensive medication at the time of presentation. Using logistic regression, we assessed the association of early follow-up care (within 7 d) and basic care (8-30 d), compared with no care within 30 days, on patient use of a new evidence-based antihypertensive medication 1 year later.

RESULTS

Our study included 2088 patients with a new diagnosis of hypertension (the first cohort), and 6420 patients in the second cohort. Of patients with new diagnoses, 48.2% and 30.2% obtained early and basic follow-up care, respectively, compared with 50.0% and 30.9% of patients in the second cohort. Compared with patients without follow-up care within 30 days, the adjusted odds of filling an evidence-based antihypertensive medication prescription 1 year later in the incident group were 2.36 (95% confidence interval [CI] 1.86-2.99) for those who received early care, and 2.00 (95% CI 1.55-2.58) for those who received basic care. The adjusted odds in the second cohort were 2.12 (95% CI 1.84-2.43) and 1.96 (95% CI 1.69-2.27), respectively.

INTERPRETATION

Early follow-up care after leaving an emergency department with a diagnosis of hypertension was associated with improved long-term use of evidence-based antihypertensive medication. As patients increasingly present to the emergency department for hypertension, a formal, timely follow-up care system could improve patient use of evidence-based antihypertensive medication.

摘要

背景

超过25%的人口患有高血压。在过去十年中,急诊科寻求高血压治疗的患者数量增加了60%以上,其中不到10%的患者随后入院。主治医生建议对从急诊科出院的患者进行早期随访,但评估随访对患者预后的影响或时机的文献较少。

方法

采用基于人群的队列设计,我们纳入了2007年至2014年间从安大略省急诊科出院、主要诊断为高血压的65岁以上患者。我们确定了两个队列:一个新发队列,以及一个在就诊时使用不超过一类循证抗高血压药物的队列。使用逻辑回归,我们评估了早期随访护理(7天内)和基本护理(8 - 30天)与30天内无护理相比,对患者一年后使用新的循证抗高血压药物的影响。

结果

我们的研究包括2088例新诊断为高血压的患者(第一个队列)和6420例第二个队列的患者。在新诊断的患者中,分别有48.2%和30.2%获得了早期和基本随访护理,而第二个队列中的患者这一比例分别为50.0%和30.9%。与30天内无随访护理的患者相比,在新发组中,一年后接受早期护理的患者开具循证抗高血压药物处方的调整后优势比为2.36(95%置信区间[CI] 1.86 - 2.99),接受基本护理的患者为2.00(95% CI 1.55 - 2.58)。在第二个队列中,调整后优势比分别为2.12(95% CI 1.84 - 2.43)和1.96(95% CI 1.69 - 2.27)。

解读

诊断为高血压后从急诊科出院进行早期随访护理与循证抗高血压药物的长期使用改善相关。随着越来越多的患者因高血压前往急诊科就诊,一个正式、及时的随访护理系统可以改善患者对循证抗高血压药物的使用。

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