The effects of chlorbutol on skeletal muscle sarcoplasmic reticulum function in porcine malignant hyperpyrexia.
作者信息
Sim A T, White M D, Denborough M A
机构信息
Department of Medicine and Clinical Science, John Curtin School of Medical Research, Australian National University, Canberra.
出版信息
Int J Biochem. 1987;19(9):827-30. doi: 10.1016/0020-711x(87)90241-2.
PMID:2961634
Abstract
- Chlorbutol, a muscle relaxant, inhibits the in vitro muscle hypercontractility which is characteristic of the anaesthetic complication, malignant hyperpyrexia (MH). 2. Studies on isolated sarcoplasmic reticulum vesicles have shown that this effect of chlorbutol in MH is not due to a modification of Ca2+-transport mechanisms.
摘要
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