Department of Physiological Sciences, Faculty of Natural Sciences, Stellenbosch University, Western Cape, Stellenbosch, 7600, Republic of South Africa.
BMC Public Health. 2018 Apr 4;18(1):453. doi: 10.1186/s12889-018-5378-9.
Sufficient evidence associate body shape to detrimental lifestyle diseases including the metabolic syndrome (MetS). The prevalence of the MetS, as well as effects of the MetS and body shape on body composition, insulin-like growth factor-1 (IGF-1), C-reactive protein (CRP) and sex hormone parameters were investigated in a female farm worker population in the Western Cape.
Women between the ages of 20-60 years were classified according to the International Diabetes Federation's definition of the MetS. Assessments included body shape (android/gynoid), blood pressure, anthropometric, bioelectrical impedance analyses and blood analyses for fasting glucose and insulin, lipid profile, IGF-1, CRP, and sex hormone parameters.
The prevalence of the MetS was 52%, with abdominal obesity 68.8%, hypertension 66.4% and low high density lipoprotein-cholesterol (HDL-c) levels (64.1%) being the more prevalent MetS risk factors. The MetS, irrespective of body shape, was found to be associated with body mass index (p < 0.01), fat mass (%) (p < 0.01), waist circumference (p < 0.001), HDL-c (p < 0.001), systolic blood pressure (p < 0.05) and diastolic blood pressure (p < 0.01). No significant differences were observed for IGF-1, CRP and sex hormone parameters.
The prevalence of the MetS and its individual risk factors were found to be significantly high in this female farm worker population. Additionally, the study showed that the MetS, body shape and/or both could predict differences in body composition, physiological and biochemical parameters in women.
大量证据表明，体型与代谢综合征（MetS）等不良生活方式疾病有关。本研究旨在调查西开普省女性农场工人中代谢综合征的流行情况，以及代谢综合征及其体型对人体成分、胰岛素样生长因子-1（IGF-1）、C 反应蛋白（CRP）和性激素参数的影响。
本研究根据国际糖尿病联合会（IDF）对代谢综合征的定义，对年龄在 20-60 岁之间的女性进行分类。评估内容包括体型（安卓/女性型）、血压、人体测量学、生物电阻抗分析和空腹血糖及胰岛素、血脂谱、IGF-1、CRP 及性激素参数的血液分析。
代谢综合征的患病率为 52%，其中腹型肥胖占 68.8%，高血压占 66.4%，低高密度脂蛋白胆固醇（HDL-c）水平（64.1%）是更为普遍的代谢综合征危险因素。无论体型如何，代谢综合征都与体重指数（p<0.01）、体脂百分比（p<0.01）、腰围（p<0.001）、HDL-c（p<0.001）、收缩压（p<0.05）和舒张压（p<0.01）有关。IGF-1、CRP 和性激素参数无显著差异。
本研究发现，该女性农场工人群体中代谢综合征及其各危险因素的患病率显著较高。此外，该研究表明，代谢综合征、体型和/或两者都可以预测女性人体成分、生理和生化参数的差异。
