绝经后女性激素状态与代谢综合征之间的相关性
Correlation between Hormonal Statuses and Metabolic Syndrome in Postmenopausal Women.
作者信息
Ziaei Saeideh, Mohseni Hajar
机构信息
Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran.
出版信息
J Family Reprod Health. 2013 Jun;7(2):63-6.
Abstract
OBJECTIVE
To compare the hormonal status in postmenopausal women with and without metabolic syndrome.
MATERIALS AND METHODS
In this cross sectional study 110 postmenopausal women were enrolled. Participants completed a questionnaire and underwent a medical exam and serum evaluation for serum lipids including cholesterol (Chol), high density lipoprotein cholesterol (HDL), low density lipoprotein (LDL), triglyceride (TG), fasting blood sugar (FBS), sex hormone binding globulin (SHBG), estradiol and testosterone. Metabolic syndrome was defined according to the definition of the National Cholesterol Education Program- Adult Treatment Panel III. In this study P value less than 0.05 was accepted as significant.
RESULTS
There were significant differences between the two groups of participants with and without metabolic syndrome in age, years after menopause, BMI, weight, SHBG and testosterone (p< 0.01).
CONCLUSION
SHBG and testosterone are the most significant correlated factors to metabolic syndrome in postmenopausal women.
摘要
目的
比较患有和未患有代谢综合征的绝经后女性的激素状态。
材料与方法
在这项横断面研究中，招募了110名绝经后女性。参与者完成了一份问卷，并接受了医学检查以及血清脂质评估，包括胆固醇（Chol）、高密度脂蛋白胆固醇（HDL）、低密度脂蛋白（LDL）、甘油三酯（TG）、空腹血糖（FBS）、性激素结合球蛋白（SHBG）、雌二醇和睾酮。代谢综合征根据美国国家胆固醇教育计划成人治疗小组第三次报告的定义来界定。在本研究中，P值小于0.05被视为具有显著性。
结果
患有和未患有代谢综合征的两组参与者在年龄、绝经年限、体重指数、体重、SHBG和睾酮方面存在显著差异（p<0.01）。
结论
SHBG和睾酮是绝经后女性代谢综合征最显著的相关因素。
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