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本文引用的文献

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The metabolic syndrome: validity and utility of clinical definitions for cardiovascular disease and diabetes risk prediction.代谢综合征:心血管疾病和糖尿病风险预测的临床定义的有效性和实用性。
Maturitas. 2010 Feb;65(2):117-21. doi: 10.1016/j.maturitas.2009.11.026. Epub 2009 Dec 23.
2
Menopause is an independent predictor of metabolic syndrome in Iranian women.绝经是伊朗女性代谢综合征的独立预测因子。
Maturitas. 2010 Mar;65(3):262-6. doi: 10.1016/j.maturitas.2009.11.004. Epub 2009 Dec 3.
3
Obesity, metabolic complications and the menopause: an opportunity for prevention.肥胖、代谢并发症与绝经:预防的契机。
Climacteric. 2010 Jun;13(3):203-9. doi: 10.3109/13697130903296909.
4
Hyperinsulinaemia, a key factor of the metabolic syndrome in postmenopausal women.高胰岛素血症是绝经后女性代谢综合征的关键因素。
Maturitas. 2009 Apr 20;62(4):362-5. doi: 10.1016/j.maturitas.2008.11.026. Epub 2009 Jan 7.
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Metabolic syndrome: prevalence, associated factors, and C-reactive protein: the MADRIC (MADrid RIesgo Cardiovascular) Study.代谢综合征:患病率、相关因素及C反应蛋白:马德里心血管风险(MADRIC)研究
Metabolism. 2008 Sep;57(9):1232-40. doi: 10.1016/j.metabol.2008.04.017.
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Risks of CHD identified by different criteria of metabolic syndrome and related changes of adipocytokines in elderly postmenopausal women.不同代谢综合征标准所识别的冠心病风险及老年绝经后女性脂肪细胞因子的相关变化
J Diabetes Complications. 2007 Sep-Oct;21(5):315-9. doi: 10.1016/j.jdiacomp.2006.03.005.
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Prevalence of metabolic syndrome during menopausal transition Tehranian women: Tehran Lipid and Glucose Study (TLGS).德黑兰女性绝经过渡期代谢综合征的患病率:德黑兰血脂与血糖研究(TLGS)
Maturitas. 2007 Oct 20;58(2):150-5. doi: 10.1016/j.maturitas.2007.07.002. Epub 2007 Sep 4.
8
Low sex hormone-binding globulin is associated with the metabolic syndrome in postmenopausal women.低性激素结合球蛋白与绝经后女性的代谢综合征相关。
Metabolism. 2006 Nov;55(11):1473-80. doi: 10.1016/j.metabol.2006.06.017.
9
Sex-hormone-binding globulin and the free androgen index are related to cardiovascular risk factors in multiethnic premenopausal and perimenopausal women enrolled in the Study of Women Across the Nation (SWAN).性激素结合球蛋白和游离雄激素指数与参加全国女性健康研究(SWAN)的多种族绝经前和围绝经期女性的心血管危险因素相关。
Circulation. 2005 Mar 15;111(10):1242-9. doi: 10.1161/01.CIR.0000157697.54255.CE.
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Glucose and insulin components of the metabolic syndrome are associated with hyperandrogenism in postmenopausal women: the atherosclerosis risk in communities study.代谢综合征的葡萄糖和胰岛素成分与绝经后女性的高雄激素血症相关:社区动脉粥样硬化风险研究
Am J Epidemiol. 2004 Sep 15;160(6):540-8. doi: 10.1093/aje/kwh250.

绝经后女性激素状态与代谢综合征之间的相关性

Correlation between Hormonal Statuses and Metabolic Syndrome in Postmenopausal Women.

作者信息

Ziaei Saeideh, Mohseni Hajar

机构信息

Faculty of Medical Science, Tarbiat Modares University, Tehran, Iran.

出版信息

J Family Reprod Health. 2013 Jun;7(2):63-6.

PMID:24971105
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4064771/
Abstract

OBJECTIVE

To compare the hormonal status in postmenopausal women with and without metabolic syndrome.

MATERIALS AND METHODS

In this cross sectional study 110 postmenopausal women were enrolled. Participants completed a questionnaire and underwent a medical exam and serum evaluation for serum lipids including cholesterol (Chol), high density lipoprotein cholesterol (HDL), low density lipoprotein (LDL), triglyceride (TG), fasting blood sugar (FBS), sex hormone binding globulin (SHBG), estradiol and testosterone. Metabolic syndrome was defined according to the definition of the National Cholesterol Education Program- Adult Treatment Panel III. In this study P value less than 0.05 was accepted as significant.

RESULTS

There were significant differences between the two groups of participants with and without metabolic syndrome in age, years after menopause, BMI, weight, SHBG and testosterone (p< 0.01).

CONCLUSION

SHBG and testosterone are the most significant correlated factors to metabolic syndrome in postmenopausal women.

摘要

目的

比较患有和未患有代谢综合征的绝经后女性的激素状态。

材料与方法

在这项横断面研究中,招募了110名绝经后女性。参与者完成了一份问卷,并接受了医学检查以及血清脂质评估,包括胆固醇(Chol)、高密度脂蛋白胆固醇(HDL)、低密度脂蛋白(LDL)、甘油三酯(TG)、空腹血糖(FBS)、性激素结合球蛋白(SHBG)、雌二醇和睾酮。代谢综合征根据美国国家胆固醇教育计划成人治疗小组第三次报告的定义来界定。在本研究中,P值小于0.05被视为具有显著性。

结果

患有和未患有代谢综合征的两组参与者在年龄、绝经年限、体重指数、体重、SHBG和睾酮方面存在显著差异(p<0.01)。

结论

SHBG和睾酮是绝经后女性代谢综合征最显著的相关因素。