Fossati P
Inserm, CNRS, institut du cerveau et de la moelle (ICM), hôpital Pitié-Salpêtrière, Sorbonne universités, UPMC université Paris 06, AP-HP, boulevard de l'Hôpital, 75013 Paris, France.
Rev Neurol (Paris). 2018 Apr;174(4):212-215. doi: 10.1016/j.neurol.2018.01.365. Epub 2018 Apr 2.
This is a review of cognitive abilities in major depression, which is associated with attention problems, memory deficit and wide impairment in executive functions. Depressed patients show two major cognitive biases: excessive processing of negatively valenced emotional stimuli; and increased self-focus. Both of these biases help to facilitate the integration of negative self-related information in depressed patients and to maintain their negative mood. Brain imaging studies suggest that this cognitive impairment is characterized by abnormal cooperation between the cognitive and limbic networks involved in cognitive control and self-referential processing. In general, depression is a disorder of multiple networks with emotional, cognitive and emotional symptoms. Among these symptoms, cognition is a major determinant of functional and social outcomes.
这是一篇关于重度抑郁症认知能力的综述，重度抑郁症与注意力问题、记忆缺陷以及执行功能的广泛受损有关。抑郁症患者表现出两种主要的认知偏差：对负性情绪刺激的过度加工；以及自我关注增加。这两种偏差都有助于促进抑郁症患者整合与自我相关的负面信息，并维持他们的负面情绪。脑成像研究表明，这种认知障碍的特征是参与认知控制和自我参照加工的认知网络和边缘系统网络之间的异常协作。一般来说，抑郁症是一种涉及情绪、认知和情感症状的多网络障碍。在这些症状中，认知是功能和社会结果的主要决定因素。
