Neuropsychology and Cognitive Neuroscience Laboratory, Department of Neuroscience, Imaging and Clinical Sciences, G. D'Annunzio University.
Neuroimaging Laboratory, Department of Physiology and Pharmacology, Sapienza University.
Neuropsychology. 2018 Mar;32(3):269-279. doi: 10.1037/neu0000409.
Personal neglect (PN) is the hemi-inattention toward the contralesional bodily space that follows a cerebral lesion, usually to the right hemisphere.
To provide a historical, comprehensive review of the different theoretical accounts, of the available diagnostic measures, of the relationship with different body representation disorders, and of recovery-related issues. Moreover, to review the anatomo-functional correlates of PN, focusing on group studies that used modern voxel-based lesion-symptoms mapping.
PubMed database was searched for all the available studies on PN conducted in the last 30 years. Relevant clinical data for each study were reported in a table, which was used as a reference for developing the discussion on the points of interest.
Evaluation tools for PN suffer from limitations and should include both face- and body-related testing as well as require both basic exploration and object use in the same personal space. Dedicated rehabilitative procedures are lacking and advocated, given that recovery of PN and extrapersonal neglect can be dissociated and their degree is not correlated. PN is almost constantly associated with a cohort of body representation disorders that do not reveal themselves unless specifically investigated. PN is significantly correlated to alterations at the level of both the anterior parietal cortex and the underlying fronto-parietal fiber bundles.
The discussed data point to the need for a diagnostic and rehabilitative update. Following the topological and hodological lesional pattern, PN might emerge from the combination of a body representation disorder and a spatial inattention for half of the space. (PsycINFO Database Record
个人忽视（PN）是指大脑损伤后对身体对侧空间的单侧忽略，通常发生在右半球。
提供个人忽视的不同理论解释、现有诊断措施、与不同身体代表障碍的关系以及与恢复相关问题的历史、全面综述。此外，还回顾了 PN 的解剖功能相关性，重点研究了使用现代基于体素的病变症状映射的组研究。
在过去 30 年中，在 PubMed 数据库中搜索了所有关于 PN 的研究。将每个研究的相关临床数据报告在一个表中，该表用作讨论感兴趣点的参考。
PN 的评估工具存在局限性，应包括面部和身体相关测试，并需要在相同的个人空间中进行基本探索和物体使用。缺乏专门的康复程序，并提倡使用，因为 PN 和外忽视的恢复可以分离，而且它们的程度没有相关性。PN 几乎总是与一组身体代表障碍相关联，除非进行专门调查，否则这些障碍不会显现出来。PN 与前顶叶皮层和底层额顶叶纤维束的改变显著相关。
讨论的数据表明需要进行诊断和康复更新。根据拓扑和轨迹病变模式，PN 可能是身体代表障碍和对一半空间的空间注意力不集中的组合导致的。
