Kurz Jacqueline P, Schoenhals Kate E, Hullinger Gordon A, Van Wettere Arnaud J
School of Veterinary Medicine, Department of Animal, Dairy, and Veterinary Sciences, Utah State University, Logan, UT 84341, USA.
Utah Veterinary Diagnostic Laboratory, Logan, UT 84341, USA.
Vet Sci. 2018 Apr 5;5(2):39. doi: 10.3390/vetsci5020039.
Syringomyelia is a form of myelodysplasia defined by the formation of one or more fluid-filled cavities within the spinal cord that do not communicate with the central canal. The defect may be congenital or acquired. Clinical signs correlate to the segment of spinal cord affected and include pain, paresis, proprioceptive deficits, alterations in sensation, scoliosis, and autonomic dysfunction. This report describes the clinical and pathologic changes in a case of acquired syringomyelia in a 10-year-old American Paint Horse mare. The horse had a six-week history of progressive proprioceptive deficits in all four limbs, bilateral pelvic limb ataxia, and muscle fasciculations that were unresponsive to treatment with stall rest, phenylbutazone, and dexamethasone. Syringomyelia was diagnosed postmortem within cervical, thoracic, and lumbar spinal cord segments. Acquired syringomyelia should be considered among differential diagnoses in adult horses displaying progressive neurologic deficits.
脊髓空洞症是一种脊髓发育异常的形式，其定义为脊髓内形成一个或多个与中央管不相连的充满液体的腔隙。该缺陷可能是先天性的或后天获得性的。临床症状与受影响的脊髓节段相关，包括疼痛、轻瘫、本体感觉缺陷、感觉改变、脊柱侧弯和自主神经功能障碍。本报告描述了一匹10岁美国花马母马后天性脊髓空洞症病例的临床和病理变化。这匹马有六周的病史，表现为四肢进行性本体感觉缺陷、双侧后肢共济失调以及肌肉束颤，对休息、苯基丁氮酮和地塞米松治疗无反应。死后在颈、胸和腰脊髓节段诊断出脊髓空洞症。对于表现出进行性神经功能缺损的成年马匹，鉴别诊断时应考虑后天性脊髓空洞症。
