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哮喘知识、护理和妊娠结局:QAKCOP 研究。

Asthma knowledge, care, and outcome during pregnancy: The QAKCOP study.

机构信息

1 Department of Medicine, Hamad General Hospital and Weill-Cornell Medical College, Doha, Qatar.

2 Department of Medicine, Hamad General Hospital, Doha, Qatar.

出版信息

Chron Respir Dis. 2019 Jan-Dec;16:1479972318767719. doi: 10.1177/1479972318767719. Epub 2018 Apr 5.

Abstract

Asthma is the most common chronic medical condition affecting pregnancy. Optimizing asthma management in pregnancy is paramount for the well-being of both the mother and the baby. The primary objectives of this study were to assess patient's knowledge about asthma, the level of asthma care, and fetal and maternal outcomes among pregnant asthmatic women in this wealthy country with tremendous improvement in maternal and fetal health care. The secondary objective was to identify barriers to asthma control. This was a cross-sectional, face-to-face, prospective study of 80 pregnant women with physician-diagnosed asthma. About 56% of patients reported worsening of their asthma control during pregnancy, of which 52.3% felt this worsening in the third trimester. About 65% of patients had uncontrolled asthma during their pregnancy, and inhaler technique was incorrect in 64.4%. Only 38% of patients knew the difference between controller and reliever asthma medications, 12.7% of patients had received written asthma action plan, 17% had a spirometry done in the previous 5 years, and 3.8% had peak expiratory flow meter at home. The main reasons for uncontrolled asthma were lack of knowledge about right asthma medications in 30% and fear of side effects of inhaled corticosteroids in 19% of patients. No financial reason was reported. Significant associations between total number of pregnancies, poor perception of asthma medications, asthma exacerbation during delivery and poor asthma control were observed. Preeclampsia and congenital anomalies occurred at higher rates than previously reported among general population in this country. The tremendous improvements in maternal health care and socioeconomic status do not seem to be a barrier to the globally recognized poor asthma care in pregnancy. Important strategies are much needed.

摘要

哮喘是影响妊娠的最常见慢性疾病。优化妊娠期间的哮喘管理对母亲和婴儿的健康至关重要。本研究的主要目的是评估哮喘患者的知识水平、哮喘管理水平以及在这个孕产妇保健水平大幅提高的富裕国家中,妊娠哮喘女性的母婴结局。次要目的是确定哮喘控制的障碍。这是一项针对 80 名经医生诊断患有哮喘的孕妇的横断面、面对面、前瞻性研究。约 56%的患者报告在妊娠期间哮喘控制恶化,其中 52.3%在孕晚期感到恶化。约 65%的患者在妊娠期间哮喘未得到控制,64.4%的患者吸入器技术不正确。只有 38%的患者知道控制和缓解哮喘药物的区别,12.7%的患者接受过书面哮喘行动计划,17%的患者在过去 5 年内进行过肺功能检查,3.8%的患者在家中使用峰流速仪。哮喘未得到控制的主要原因是 30%的患者对正确的哮喘药物缺乏了解,19%的患者担心吸入皮质类固醇的副作用。没有患者报告经济原因。观察到总妊娠次数、对哮喘药物的不良认知、分娩期间哮喘恶化与哮喘控制不良之间存在显著相关性。子痫前期和先天畸形的发生率高于该国一般人群的先前报告。孕产妇保健和社会经济地位的巨大改善似乎并不是全球公认的妊娠期间哮喘管理不佳的障碍。非常需要采取重要策略。

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