Abdulkader Zeyad Mohannad, Ur Rahman Sajjad, Nimeri Nuha
Royal College of Physicians, Dublin, Ireland.
NICU Women's Hospital, Hamad Medical Corporation, Doha, Qatar.
Qatar Med J. 2013 Nov 1;2012(2):32-7. doi: 10.5339/qmj.2012.2.10. eCollection 2012.
To analyze the association between maternal ethnicity and gestational age with the incidence of low birth weight and intrauterine growth restriction.
Prospective, analytic study Methods: The study was conducted between March 14th and April 4th 2011 in Women's Hospital HMC. The data was ascertained from the delivery register of labor ward on daily basis using predesigned, structured questionnaire. Data was stratified according to the maternal ethnicity groups and gestational age at birth (term and preterm).
The total deliveries during the study period were 890; 35.5% Qatari (n 316) and 64.5% non-Qatari (n 574). The incidence of LBW was 12.36% (n 110). The difference of LBW incidence between Qatari (13.6% n 43) and non-Qatari (11.67% n 67) groups was non significant (RR 1.17, 95% CI 0.82-1.67, p = 0.401). The same was between non-Qatari sub groups (p < 0.05). The incidence of IUGR was 6% (n 54; 49.09% of LBW). The incidence of IUGR between Qatari (5.7% n 18) and non-Qatari (6.27% n 36) groups was significant (RR 0.45, 95% CI 0.3-0.6 p>0.05). The incidence of LBW was 7.85% (n 60) in term babies and 39.68% (n 50) in preterm babies. The incidence if IUGR was 3.79% (n 29) in term babies and 19.84% (n 25) in preterm babies. Preterm babies had a five times higher risk of both being LBW (RR 5.05; 95%CI 3.65-6.99; p < 0.001) and IUGR (RR 5.23; 95% CI 3.17-8.62; p < 0.001).
The incidence of low birth weight is independent of maternal ethnicity in Qatar. However, the incidence of IUGR is significantly higher among the non-Qatari population. The relative risk of being LBW or IUGR is five times higher in preterm babies. Further in depth studies are indicated.
分析母亲种族和孕周与低出生体重及宫内生长受限发生率之间的关联。
前瞻性分析研究
本研究于2011年3月14日至4月4日在哈马德医疗城妇女医院开展。使用预先设计的结构化问卷,每天从产房分娩登记册中确定数据。数据根据母亲种族群体和出生时的孕周(足月儿和早产儿)进行分层。
研究期间的分娩总数为890例;卡塔尔人占35.5%(n = 316),非卡塔尔人占64.5%(n = 574)。低出生体重的发生率为12.36%(n = 110)。卡塔尔人群(13.6%,n = 43)和非卡塔尔人群(11.67%,n = 67)之间低出生体重发生率的差异无统计学意义(相对危险度1.17,95%可信区间0.82 - 1.67,p = 0.401)。非卡塔尔亚组之间也是如此(p < 0.05)。宫内生长受限的发生率为6%(n = 54;占低出生体重儿的49.09%)。卡塔尔人群(5.7%,n = 18)和非卡塔尔人群(6.27%,n = 36)之间宫内生长受限的发生率有显著差异(相对危险度0.45,95%可信区间0.3 - 0.6,p>0.05)。足月儿低出生体重的发生率为7.85%(n = 60),早产儿为39.68%(n = 50)。足月儿宫内生长受限的发生率为3.79%(n = 29),早产儿为19.84%(n = 25)。早产儿发生低出生体重(相对危险度5.05;95%可信区间3.65 - 6.99;p < 0.001)和宫内生长受限(相对危险度5.23;95%可信区间3.17 - 8.62;p < 0.001)的风险高出五倍。
在卡塔尔,低出生体重的发生率与母亲种族无关。然而,非卡塔尔人群中宫内生长受限的发生率显著更高。早产儿发生低出生体重或宫内生长受限的相对风险高出五倍。需要进一步开展深入研究。