Post-graduate Program on Pharmaceutical Sciences, Amapá Federal University, Campus Universitário Marco Zero do Equador, Rodovia Juscelino Kubitschek de Oliveira, KM, 02-Bairro Zerão, 68902-280 Macapá, AP, Brazil; Laboratory of Phytopharmaceutical Nanobiotechnology, Amapá Federal University, Campus Universitário-Marco Zero do Equador, Rodovia Juscelino Kubitschek de Oliveira, KM, 02-Bairro, 68902-280 Macapá, AP, Brazil.
Laboratory of Phytopharmaceutical Nanobiotechnology, Amapá Federal University, Campus Universitário-Marco Zero do Equador, Rodovia Juscelino Kubitschek de Oliveira, KM, 02-Bairro, 68902-280 Macapá, AP, Brazil.
Food Chem. 2018 Aug 15;257:196-205. doi: 10.1016/j.foodchem.2018.02.067. Epub 2018 Feb 14.
The seeds of Bixa orellana L. is widely used in food industry as a natural colorant. A major technological challenge for its utilization on aqueous food products is the low water solubility. Therefore, the present study aimed to obtain aqueous nanodispersions using this natural raw material by using a simple organic solvent-free and low energy method. Bixin and geranylgeraniol were found on the extract. The nanodispersions were prepared by addition of water on a mixture of extract and surfactant (s). The effect of the surfactants and dilution on the nanodispersions were also evaluated. Best results were achieved using polysorbate 80/sorbitan monooleate (HLB 13) (diluted in water, 1:10). The results shows the potential of this ecofriendly approach, in contrast to common methods that make use of potentially toxic organic solvents and high input of energy, which elevate the costs for further industrialization.
胭脂树种子广泛应用于食品工业作为天然着色剂。在水性食品中应用的主要技术挑战是低水溶性。因此，本研究旨在通过使用简单的无有机溶剂和低能耗的方法从这种天然原料中获得水性纳米分散体。提取物中发现了胭脂树红和香叶基香叶醇。纳米分散体是通过在提取物和表面活性剂（s）的混合物中加水制备的。还评估了表面活性剂和稀释度对纳米分散体的影响。使用吐温 80/山梨醇单油酸酯（HLB 13）（在水中稀释，1:10）可获得最佳结果。结果表明，与使用可能有毒的有机溶剂和高能量输入的常见方法相比，这种环保方法具有潜力，这会增加进一步工业化的成本。
