Korem Maya, Wallach Tali, Bursztyn Michael, Maayan Shlomo, Olshtain-Pops Karen
AIDS Unit, Department of Clinical Microbiology and Infectious Diseases, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.
Department of Pediatrics, Kaplan Medical Center, Rehovot, Israel.
Int J Hypertens. 2018 Jan 29;2018:8637101. doi: 10.1155/2018/8637101. eCollection 2018.
Prevalence of hypertension has not been studied in the Ethiopian HIV-infected population, which represents 60% of the patients in our AIDS unit. Our aim was to identify risk factors and characterize the prevalence of hypertension in the population monitored at our unit.
A retrospective chart review categorized subjects according to their blood pressure levels. Hypertension prevalence was determined and stratified according to variables perceived to contribute to elevated blood pressure.
The prevalence of hypertension in our study population was significantly higher compared to the general population (53% versus 20%, < 0.0001) and was associated with known risk factors and not with patients' viral load and CD4 levels. Ethiopian HIV-infected adults had a prominently higher rate of blood pressure rise over time as compared to non-Ethiopians ( = 0.016).
The high prevalence of hypertension in this cohort and the rapid increase in blood pressure in Ethiopians are alarming. We could not attribute high prevalence to HIV-related factors and we presume it is part of the metabolic syndrome. The lifelong cardiovascular risk associated with HIV infection mandates hypertension screening and close monitoring in this population.
埃塞俄比亚艾滋病毒感染人群中高血压的患病率尚未得到研究,该人群占我们艾滋病科室患者的60%。我们的目的是确定风险因素,并描述在我们科室接受监测的人群中高血压的患病率特征。
通过回顾性病历审查,根据受试者的血压水平对其进行分类。确定高血压患病率,并根据被认为会导致血压升高的变量进行分层。
我们研究人群中高血压的患病率显著高于一般人群(53%对20%,<0.0001),并且与已知风险因素相关,与患者的病毒载量和CD4水平无关。与非埃塞俄比亚人相比,埃塞俄比亚艾滋病毒感染成年人随着时间推移血压升高的速率明显更高(=0.016)。
该队列中高血压的高患病率以及埃塞俄比亚人血压的快速升高令人担忧。我们无法将高患病率归因于与艾滋病毒相关的因素,我们推测这是代谢综合征的一部分。与艾滋病毒感染相关的终身心血管风险要求对该人群进行高血压筛查和密切监测。