Kalkur Chaithra, Sattur Atul P, Guttal Kruthika S, Lakshman Anusha R
a Department of Oral Medicine & Radiology , Century International Institute of Dental Science & Research Centre , Poinachi, Kasargod , Kerala , India.
b Department of Oral Medicine & Radiology , S.D.M College of Dental Sciences and Hospital , Sattur, Dharwad , Karnataka , India.
J Diet Suppl. 2019;16(2):207-214. doi: 10.1080/19390211.2018.1448922. Epub 2018 Apr 6.
Oral submucous fibrosis (OSMF) is one of the "diseases of civilization" because of the large differences in prevalence among races, geographic areas, and individuals at different socioeconomic levels. It is a premalignant condition strongly associated with the habit of chewing areca nuts. This study is to compare the scoring system in relation to the burning sensation of mouth and dysphagia using the visual analog scale (VAS) and Dakkak and Bennett grading system for Indian food, respectively, in OSMF patients. This study was a randomized clinical trial incorporating a total of 50 cases of OSMF divided into a control group (antioxidant therapy) and pentoxifylline test cases. Values for burning sensation of the mouth using the VAS and modified Dakkak and Bennett grading system for Indian food were recorded. Statistical analyses were done using t test, Mann -Whitney U test, and one-way analysis of variance (ANOVA) test. Patients subjected to pentoxifylline when compared to the control group showed significant reduction in dysphagia for Indian food. Burning sensation was recorded according to the visual analogue scale. Significant reduction in burning sensation was seen in the pentoxifylline group when compared to the control group. This grading system provides quantitative and qualitative parameters in patients with OSMF.
口腔黏膜下纤维化(OSMF)是一种“文明病”,因为在不同种族、地理区域以及不同社会经济水平的个体之间,其患病率存在巨大差异。它是一种与咀嚼槟榔习惯密切相关的癌前病变。本研究旨在分别使用视觉模拟量表(VAS)以及针对印度食物的达卡克和贝内特分级系统,比较口腔烧灼感和吞咽困难方面的评分系统,研究对象为OSMF患者。本研究为一项随机临床试验,共纳入50例OSMF病例,分为对照组(抗氧化治疗)和己酮可可碱试验组。记录使用VAS评估的口腔烧灼感值以及针对印度食物的改良达卡克和贝内特分级系统的结果。采用t检验、曼 - 惠特尼U检验和单因素方差分析(ANOVA)进行统计分析。与对照组相比,接受己酮可可碱治疗的患者在食用印度食物时吞咽困难明显减轻。根据视觉模拟量表记录烧灼感。与对照组相比,己酮可可碱组的烧灼感明显减轻。该分级系统为OSMF患者提供了定量和定性参数。