Wilson Stacey L, Adam Jamila K, Krishna Suresh Babu Naidu
Department of Biomedical & Clinical Technology, M L Sultan Campus, Durban-4000, Republic of South Africa.
Afr J Reprod Health. 2017 Sep;21(3):96-101. doi: 10.29063/ajrh2017/v21i3.9.
Vaginal lubricants are used to solve intercourse difficulties or as sexual enhancers, but recent reports raise questions about their safety in terms of fertility. In this study, twenty semen samples were tested against commercially available vaginal lubricants for progressive spermatozoa motility and vitality with varying exposure time intervals. Results showed that the vaginal lubricant which least affected progressive spermatozoa motility was the oil-based vaginal lubricant, which kept the mean percentage of progressive spermatozoa motility within the minimum normal range of 32%, following 60 minutes of exposure. The silicone-based vaginal lubricant produced similar results to the oil-based vaginal lubricant, however the progressive spermatozoa motility dropped below the minimum normal range within 60 minutes of exposure. The fertility lubricant did not produce mean progressive motilities that were within the normal minimum range at any of the three time intervals, producing poor results overall. The vaginal lubricant which produced the poorest results was the water-based, which immobilized all of the spermatozoa within 5 minutes of exposure and killed on average 95.23% within 60 minutes. Although further assessment is required, these results highlight potential fertility issues related to the formulation of commercially available vaginal lubricants.
阴道润滑剂用于解决性交困难或作为性增强剂，但最近的报告就其在生育方面的安全性提出了疑问。在本研究中，针对市售阴道润滑剂，在不同暴露时间间隔下，对20份精液样本进行了精子前向运动能力和活力测试。结果显示，对精子前向运动能力影响最小的阴道润滑剂是油基阴道润滑剂，在暴露60分钟后，其精子前向运动能力的平均百分比保持在32%的最低正常范围内。硅基阴道润滑剂产生了与油基阴道润滑剂相似的结果，然而，在暴露60分钟内，精子前向运动能力降至最低正常范围以下。生育润滑剂在三个时间间隔中的任何一个时间都没有产生处于正常最低范围内的平均前向运动能力，总体结果较差。产生最差结果的阴道润滑剂是水基润滑剂，它在暴露5分钟内使所有精子失去活力，在60分钟内平均杀死95.23%的精子。尽管需要进一步评估，但这些结果突出了与市售阴道润滑剂配方相关的潜在生育问题。
