Laboratorio de Electroquímica del Medio Ambiente (LEQMA), Departamento de Química de los Materiales, Facultad de Química y Biología, Universidad de Santiago de Chile (USACH), Casilla 40, Correo 33, Santiago, Chile.
Departamento de Ingeniería Química, Laboratorio de Biotecnología Ambiental, Facultad de Ingeniería, Universidad de Santiago de Chile (USACH), Chile.
Sci Total Environ. 2018 May 15;624:1095-1105. doi: 10.1016/j.scitotenv.2017.12.159. Epub 2017 Dec 27.
The elimination of the antibiotic Nafcillin (NAF), which is usually used in hospitals and veterinary clinics around the world, was assessed through a combination of three advanced electrochemical oxidation processes followed by anaerobic digestion process. In the first stage different electrochemical advanced oxidation processes (EAOPs) were used: electro-oxidation with hydrogen peroxide (EO-HO), electro-Fenton (EF) and Photo electro-Fenton (PEF). After PEF, almost complete and highly efficient degradation and elimination of NAF was achieved, with the concomitant elimination of the associated antimicrobial activity. The fast degradation rate produced by PEF is explained by the oxidative action of hydroxyl radicals (•OH) together with the direct UV photolysis of complexes formed between Fe and some organic intermediates. Total removal of NAF occurs after 90min of electrolysis by PEF, with the generation of organic intermediates that remain in solution. However, when this post PEF process solution was treated with an anaerobic biological process, the intermediates generated in the electrochemical degradation of NAF were completely eliminated after 24h. The kinetic degradation of NAF as well as the identification/quantification of products and intermediates formed during the degradation of antibiotic, such as inorganic ions, carboxylic acids and aromatic compounds, were determined by chromatographic and photometric methods. Finally, an oxidation pathway is proposed for the complete conversion to CO.
通过三种先进的电化学氧化工艺（电氧化双氧水（EO-HO）、电芬顿（EF）和光电芬顿（PEF））的组合，评估了在全球医院和兽医诊所常用的抗生素萘夫西林（NAF）的消除情况。在第一阶段，使用了不同的电化学高级氧化工艺（EAOPs）：过氧化氢电氧化（EO-HO）、电芬顿（EF）和光电芬顿（PEF）。在 PEF 之后，几乎完全且高效地实现了 NAF 的降解和消除，同时消除了相关的抗菌活性。PEF 产生的快速降解速率可归因于羟基自由基（•OH）的氧化作用以及 Fe 与一些有机中间产物形成的复合物的直接 UV 光解。通过 PEF 电解 90 分钟后，可完全去除 NAF，同时生成仍留在溶液中的有机中间产物。然而，当对 PEF 后的工艺溶液进行厌氧生物处理时，在电化学降解 NAF 过程中生成的中间产物在 24 小时后完全消除。通过色谱和光度法确定了 NAF 的动力学降解以及抗生素降解过程中形成的产物和中间产物（如无机离子、羧酸和芳香族化合物）的鉴定/定量。最后，提出了一种将其完全转化为 CO 的氧化途径。
