大肠杆菌蛋白YbgI的潜在作用

Possible Role of Escherichia coli Protein YbgI.

作者信息

Sergeeva O V, Bredikhin D O, Nesterchuk M V, Serebryakova M V, Sergiev P V, Dontsova O A

机构信息

Skolkovo Institute of Science and Technology, 143026 Skolkovo, Moscow Region, Russia.

出版信息

Biochemistry (Mosc). 2018 Mar;83(3):270-280. doi: 10.1134/S0006297918030070.

DOI:10.1134/S0006297918030070

PMID:29625546

Abstract

Proteins containing the NIF3 domain are highly conserved and are found in bacteria, eukaryotes, and archaea. YbgI is an Escherichia coli protein whose gene is conserved among bacteria. The structure of YbgI is known; however, the function of this protein in cells remains obscure. Our studies of E. coli cells with deleted ybgI gene suggest that YbgI is involved in formation of the bacterial cell wall.

摘要

含有NIF3结构域的蛋白质高度保守，存在于细菌、真核生物和古细菌中。YbgI是一种大肠杆菌蛋白，其基因在细菌中保守。YbgI的结构已知，然而，该蛋白在细胞中的功能仍不清楚。我们对缺失ybgI基因的大肠杆菌细胞的研究表明，YbgI参与细菌细胞壁的形成。