Li Guanqun, Lee Matthew S, Kraft Kate H, Heider Amer
State University of New York Upstate Medical University, Syracuse, NY.
Department of Urology, University of Michigan, Ann Arbor, MI.
Urology. 2018 Jul;117:145-149. doi: 10.1016/j.urology.2018.03.033. Epub 2018 Apr 4.
An otherwise healthy 7-year-old boy was diagnosed with malignant large cell calcifying Sertoli cell tumor (LCCSCT) of the testis. He underwent attempted partial orchiectomy with conversion to radical orchiectomy due to suspected malignancy on intraoperative frozen section. There was no lymph node or visceral metastases. To our knowledge, this is the first report of malignant LCCSCT in the prepubertal population. LCCSCT of the testis is an extremely rare neoplasm, with low malignant potential. Malignant cases are exclusively reported previously in the adult population. We report the first case of malignant LCCSCT in a pediatric patient. We review the literatures and discuss the clinical, pathologic features and treatments of malignant LCCSCT.
一名原本健康的7岁男孩被诊断为睾丸恶性大细胞钙化性支持细胞瘤（LCCSCT）。由于术中冰冻切片怀疑为恶性肿瘤，他接受了部分睾丸切除术，但因术中情况转为根治性睾丸切除术。未发现淋巴结或内脏转移。据我们所知，这是青春期前人群中恶性LCCSCT的首例报告。睾丸LCCSCT是一种极其罕见的肿瘤，恶性潜能低。此前仅在成年人群中报告过恶性病例。我们报告了首例儿科患者的恶性LCCSCT病例。我们回顾了文献并讨论了恶性LCCSCT的临床、病理特征及治疗方法。
