Bardisi Mahmoud, Khabaz Mohamad Nidal, Al-Maghrabi Jaudah Ahmad
Riyadh Regional Lab and Blood Bank, Ministry of Health, Riyadh, Saudi Arabia.
Department of Pathology, Rabigh Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Case Rep Pathol. 2020 Mar 18;2020:5279013. doi: 10.1155/2020/5279013. eCollection 2020.
Large cell calcifying Sertoli cell tumors (LCCSCTs) are extremely rare, with less than 100 tumors being described to date. Most of the tumors are benign with a few malignant cases, and aggressive behavior is infrequent. These tumors are a type of Sertoli cell tumor, and these tumors comprise less than 0.3% of all testis tumors in Saudi Arabia. They usually occur in boys and young adults and can affect one or both testicles in multifocal form causing microcalcifications. A 28-year-old male visited our hospital with left testis pain. Physical examination of the scrotum revealed that both testicles were normal sized with no palpable mass. Ultrasonography evaluation revealed grade 3 left varicocele and an incidental 9 mm calcified mass in the right testicle, which was further confirmed by MRI. Partial orchiectomy was performed. Clinical data, radiological studies, and morphological and immunohistochemical characteristics were analyzed.
大细胞钙化性支持细胞瘤（LCCSCTs）极为罕见，迄今为止报道的病例不足100例。大多数肿瘤为良性，少数为恶性，侵袭性行为并不常见。这些肿瘤属于支持细胞瘤类型，在沙特阿拉伯，它们占所有睾丸肿瘤的比例不到0.3%。它们通常发生于男孩和年轻成年人，可呈多灶性累及一侧或双侧睾丸，导致微钙化。一名28岁男性因左侧睾丸疼痛前来我院就诊。阴囊体格检查显示双侧睾丸大小正常，未触及肿块。超声检查发现左侧3级精索静脉曲张，右侧睾丸意外发现一个9毫米的钙化肿块，MRI进一步证实了这一情况。遂行睾丸部分切除术。对临床资料、影像学研究以及形态学和免疫组化特征进行了分析。
