Department of Thoracic and Cardiovascular Surgery, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio.
Department of Diagnostic Radiology, Imaging Institute, Cleveland Clinic, Cleveland, Ohio.
J Thorac Cardiovasc Surg. 2018 Aug;156(2):871-877.e2. doi: 10.1016/j.jtcvs.2018.03.001. Epub 2018 Mar 8.
The value of routine timed barium esophagram (TBE) in longitudinal follow-up of achalasia after Heller myotomy is unknown. We prospectively prescribed a yearly follow-up TBE. Purposes were to characterize esophageal emptying over time after myotomy, identify preoperative TBE measures associated with follow-up TBE, and characterize follow-up TBE over time in relationship to reintervention.
From March 1995 to April 2013, 635 patients underwent Heller myotomy for achalasia; 559 had at least 1 follow-up TBE. Temporal trends of 1335 follow-up TBEs in all nonreintervention and reintervention patients were assessed. Multivariable longitudinal analysis identified preoperative TBE measures associated with follow-up TBE.
On average, TBE height and width at 1 and 5 minutes decreased approximately 50% and 60%, respectively, at first postoperative follow-up, and remained stable or slightly decreased for up to 5 years. Wider TBE width at 5 minutes was associated with greater follow-up TBE height and width at 1 minute. Of 118 patients undergoing reintervention, 64 (57%) had only 1 reintervention, with follow-up TBE returning to that of nonreintervention patients. Patients whose follow-up TBE remained abnormal underwent a further reintervention, some normalizing on subsequent TBE, and some not.
Follow-up TBE is valuable postmyotomy, particularly if there is substantial esophageal dilatation preoperatively. Follow-up TBE reassures patients with stable or decreasing TBE measures, permitting decreased follow-up intensity. Reintervention should not be considered a myotomy failure, because a successful, single, nonsurgical reintervention often results in long-term successful palliation. More than 1 reintervention requires intensification of TBE follow-up, facilitating treatment planning.
在行 Heller 肌切开术后对贲门失弛缓症进行纵向随访时,常规定时钡餐食管造影(TBE)的价值尚不清楚。我们前瞻性地规定每年进行 TBE 随访。目的是描述肌切开术后食管排空的时间变化,确定与随访 TBE 相关的术前 TBE 指标,并描述与再次干预相关的随时间变化的 TBE 随访结果。
1995 年 3 月至 2013 年 4 月,635 例患者因贲门失弛缓症接受 Heller 肌切开术;其中 559 例至少有 1 次 TBE 随访。评估了所有非再次干预和再次干预患者的 1335 次 TBE 随访的时间趋势。多变量纵向分析确定了与随访 TBE 相关的术前 TBE 指标。
平均而言,TBE 高度和宽度在术后第 1 次随访时分别减少约 50%和 60%,在 5 年内保持稳定或略有下降。5 分钟时 TBE 宽度较宽与 1 分钟时 TBE 高度和宽度较大相关。在 118 例接受再次干预的患者中,64 例(57%)仅接受 1 次再次干预,TBE 随访结果恢复至非再次干预患者的水平。TBE 随访结果仍异常的患者再次接受了进一步的干预,一些患者的 TBE 结果恢复正常,而一些患者没有。
肌切开术后 TBE 随访很有价值,特别是在术前存在明显食管扩张的情况下。如果 TBE 测量值稳定或逐渐降低,随访结果可使患者放心,并减少随访强度。再次干预不应被视为肌切开术失败,因为成功的单次非手术再次干预通常可长期成功缓解症状。如果需要多次再次干预,则需要加强 TBE 随访,以方便治疗计划的制定。