Alvis-Zakzuk Nelson J, Díaz-Jiménez Diana, Castillo-Rodríguez Liliana, Castañeda-Orjuela Carlos, Paternina-Caicedo Ángel, Pinzón-Redondo Hernando, Carrasquilla-Sotomayor María, Alvis-Guzmán Nelson, De La Hoz-Restrepo Fernando
Observatorio Nacional de Salud, Instituto Nacional de Salud, Bogotá, Colombia.
Observatorio Nacional de Salud, Instituto Nacional de Salud, Bogotá, Colombia.
Value Health Reg Issues. 2018 Dec;17:32-37. doi: 10.1016/j.vhri.2018.01.004. Epub 2018 Apr 6.
The aim of the present study was to estimate the economic impact of chikungunya virus (CHIKV) infection in Colombia from a societal perspective.
We conducted a retrospective, bottom-up cost-of-illness study in clinically confirmed cases during the first chikungunya (CHIK) outbreak in Colombia in 2014. Direct and indirect costs were estimated per patient. Economic costs were calculated by the addition of direct costs (direct medical costs and out-of-pocket heath expenditures) and indirect cost as a result of loss of productivity.
A total of 126 patients (67 children and 59 adults) with CHIK were included. The median of the direct medical cost in children was US$257.9 (interquartile range [IQR] 121.7-563.8), and US$66.6 (IQR 26.5-317.3) for adults. The productivity loss median expenditures reached US$81.3 (IQR 72.2-203.2) per adult patient. The median economic cost in adults as a result of CHIK was US$152.9 (IQR 101.0-539.6), of which 53.2% was a result of indirect costs. Out-of-pocket expenditures comprised 3.3% of all economic costs.
Our study can help health decision makers to properly assess the burden of disease caused by CHIK in Colombia, an endemic tropical country. We recommend to strength the health information systems and to continue investing in public health measures to prevent CHIK.
本研究旨在从社会角度评估基孔肯雅病毒（CHIKV）感染在哥伦比亚造成的经济影响。
我们对2014年哥伦比亚首次基孔肯雅热（CHIK）疫情期间临床确诊的病例进行了一项回顾性、自下而上的疾病成本研究。估算了每位患者的直接和间接成本。经济成本通过将直接成本（直接医疗成本和自付医疗费用）与因生产力损失产生的间接成本相加得出。
共纳入126例基孔肯雅热患者（67名儿童和59名成人）。儿童的直接医疗成本中位数为257.9美元（四分位间距[IQR]为121.7 - 563.8美元），成人为66.6美元（IQR为26.5 - 317.3美元）。每位成年患者的生产力损失中位数支出达81.3美元（IQR为72.2 - 203.2美元）。基孔肯雅热导致的成人经济成本中位数为152.9美元（IQR为101.0 - 539.6美元），其中53.2%是间接成本造成的。自付费用占所有经济成本的3.3%。
我们的研究有助于卫生决策者正确评估基孔肯雅热在哥伦比亚这个热带流行国家所造成的疾病负担。我们建议加强卫生信息系统，并继续投资于预防基孔肯雅热的公共卫生措施。
