Karnik Tanvi, McBean Rhiannon, Hart Graeme, Newbigin Katrina
Department of Medicine, Bond University, Gold Coast, Queensland, Australia.
Wesley Medical Imaging, The Wesley Hospital, Auchenflower, Queensland, Australia.
BMJ Case Rep. 2018 Apr 7;2018:bcr-2017-224119. doi: 10.1136/bcr-2017-224119.
Routine imaging for mediastinal malignancies includes chest X-ray, CT or MRI. T1 and T2 mapping are novel MRI techniques which may have a role in expanding the assessment of internal tumour characteristics. This case report details two middle-aged women who had similar clinical presentations of mediastinal masses of comparable size and appearance when assessed with routine imaging. T1 and T2 maps were acquired on MRI to investigate whether these tumours could be further differentiated prior to surgery. T1 and T2 mapping supported suspicion for which tumour components were solid and cystic, as subsequently confirmed histologically. Furthermore, comparison between the two tumours showed native T1 values differed within the solid components by 37%, correlating to differences in proteinaceous material within the tumour types. This radiological-pathological correlation provides evidence that T1 and T2 mapping has clinical utility in the assessment and differentiation of mediastinal masses.
纵隔恶性肿瘤的常规影像学检查包括胸部X线、CT或MRI。T1和T2 mapping是新型MRI技术，可能在扩展对肿瘤内部特征的评估方面发挥作用。本病例报告详细介绍了两名中年女性，她们在接受常规影像学检查时，纵隔肿块的临床表现相似，大小和外观相当。在MRI上获取T1和T2图谱，以研究这些肿瘤在手术前是否可以进一步区分。T1和T2 mapping支持了对哪些肿瘤成分是实性和囊性的怀疑，随后经组织学证实。此外，两种肿瘤之间的比较显示，实性成分内的原生T1值相差37%，这与肿瘤类型中蛋白质物质的差异相关。这种放射学与病理学的相关性提供了证据，表明T1和T2 mapping在纵隔肿块的评估和鉴别中具有临床应用价值。
