Li Charles Xin, Goldenberg Yoni, McLean Catriona, Savio Gomes Keith
Department of Neurosurgery, The Alfred, 55 Commercial Road, Prahran, Victoria 3181, Australia.
Department of Neurosurgery, The Alfred, 55 Commercial Road, Prahran, Victoria 3181, Australia.
J Clin Neurosci. 2018 Jun;52:122-124. doi: 10.1016/j.jocn.2018.03.003. Epub 2018 Apr 5.
This case report describes the rare occurrence of two individually uncommon tumours found in synchronous manner in an otherwise healthy patient with no history of malignancy. We believe this to be the first reported case of synchronous glioblastoma and chondrosarcoma. While primary rib lesions metastasising to brain are rarely reported and primary brain lesions metastasising to rib are even rarer still, there were no previous reports in the literature of synchronous brain and rib dual primary pathology that we could identify. Unrelated dual pathology, while rare, must be considered amongst the list of differential diagnoses in patients who present with multiple lesions, and highlights the importance of separate histological confirmation prior to integrated management.
本病例报告描述了在一名无恶性肿瘤病史的健康患者中罕见地同时出现两种各自并不常见的肿瘤。我们认为这是首例同步发生胶质母细胞瘤和软骨肉瘤的报告病例。虽然原发性肋骨病变转移至脑部的报道很少，原发性脑部病变转移至肋骨的情况更为罕见，但我们在文献中未发现之前有同步性脑和肋骨双原发病理的报告。无关的双原发病理虽然罕见，但在出现多处病变的患者鉴别诊断清单中必须予以考虑，这突出了在综合治疗前进行单独组织学确诊的重要性。
