Kumar Lakshmi, Satheesan Keerthi N, Rajan Sunil, Vasu Bindu K, Paul Jerry
Department of Anaesthesiology, Amrita Institute of Medical Sciences, Amrita University, Cochin, Kerala, India.
Anesth Essays Res. 2018 Jan-Mar;12(1):199-205. doi: 10.4103/aer.AER_69_17.
Postoperative pulmonary complications (PPC) following abdominal surgery are associated with increased morbidity and poorer outcomes. We prospectively examined risk factors associated with the development of PPC in patients undergoing abdominal surgery.
The primary outcome was to determine the association of predefined risk factors in the prediction of PPC after abdominal surgery. Secondary outcomes were evaluation of outcomes of PPC.
This was a prospective study conducted in the gastrosurgical and urological units of a tertiary care referral hospital in patients undergoing abdominal surgery over a period of 6 months (November 2015-April 2016).
Relevant preoperative and intraoperative variables were recorded by the anesthesiologist in a pro forma provided. Postoperatively, data from the Intensive Care Unit (ICU) were collected from data sheets. PPC were defined according to preset criteria and outcomes of the patients including ICU stay, hospital stay, and mortality were noted.
Chi-square test was used to find the association of risk factors of PPC. Mann-Whitney test was used for continuous variables and McNemar's test for postoperative respiratory variables. A final regression analysis was performed with factors with significant association ( < 0.1).
One hundred and fifty patients were included, and 24 patients (16%) developed PPC as defined by our criteria. Emergency surgery (44.4% of PPC) and cardiac comorbidity (23.9% of PPC) were significant associations for pulmonary complications. The length of ICU and hospital stay (LOICU, LOHS) and mortality were higher in the group with pulmonary complications ( < 0.001).
Emergent surgery and cardiac comorbidities were independent predictors for the development of PPC. PPC are associated with increased LOHS, LOICU stay, and mortality.
腹部手术后的肺部并发症(PPC)与发病率增加及预后较差相关。我们前瞻性地研究了腹部手术患者发生PPC的相关危险因素。
主要结局是确定腹部手术后预测PPC的预定义危险因素之间的关联。次要结局是评估PPC的结局。
这是一项前瞻性研究,在一家三级医疗转诊医院的胃肠外科和泌尿外科进行,研究对象为接受腹部手术的患者,为期6个月(2015年11月至2016年4月)。
麻醉医生在提供的表格中记录相关的术前和术中变量。术后,从重症监护病房(ICU)的数据表中收集数据。根据预设标准定义PPC,并记录患者的结局,包括ICU住院时间、住院时间和死亡率。
采用卡方检验来发现PPC危险因素之间的关联。连续变量采用曼-惠特尼检验,术后呼吸变量采用麦克尼马尔检验。对具有显著关联(<0.1)的因素进行最终回归分析。
纳入150例患者,其中24例(16%)符合我们定义的PPC。急诊手术(占PPC的44.4%)和心脏合并症(占PPC的23.9%)与肺部并发症有显著关联。肺部并发症组的ICU和住院时间(LOICU、LOHS)及死亡率更高(<0.001)。
急诊手术和心脏合并症是PPC发生的独立预测因素。PPC与LOHS、LOICU住院时间增加及死亡率相关。