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麻醉持续时间、手术类型、呼吸合并症、预测的最大摄氧量和吸烟可预测上腹部手术后的肺部并发症:一项观察性研究。

Duration of anaesthesia, type of surgery, respiratory co-morbidity, predicted VO2max and smoking predict postoperative pulmonary complications after upper abdominal surgery: an observational study.

作者信息

Scholes Rebecca L, Browning Laura, Sztendur Ewa M, Denehy Linda

机构信息

Department of Physiotherapy, Faculty of Medicine, Nursing and Health Sciences, Monash University, Australia.

出版信息

Aust J Physiother. 2009;55(3):191-8. doi: 10.1016/s0004-9514(09)70081-9.

DOI:10.1016/s0004-9514(09)70081-9
PMID:19681741
Abstract

QUESTION

Can the risk of developing postoperative pulmonary complications be predicted after upper abdominal surgery?

DESIGN

Prospective observational study.

PARTICIPANTS

268 consecutive patients undergoing elective upper abdominal surgery who received standardised pre- and postoperative prophylactic respiratory physiotherapy.

OUTCOME MEASURES

Predictors were 17 preoperative and intraoperative risk factors. A postoperative pulmonary complication was diagnosed when four or more of the following criteria were present: radiological evidence of collapse/consolidation, temperature > 38 degrees C, oxyhaemoglobin saturation < 90%, abnormal sputum production, sputum culture indicating infection, raised white cell count, abnormal auscultation findings, or physician's diagnosis of pulmonary complication.

RESULTS

35 participants (13%) developed postoperative pulmonary complications. Five risk factors predicted postoperative pulmonary complications: duration of anaesthesia (OR 4.3, 95% CI 1.7 to 10.8); surgical category (OR 2.3, 95% CI 1.1 to 4.7); current smoking (OR 2.1, 95% CI 1.0 to 4.5); respiratory co-morbidity (OR 2.1, 95% CI 1.0 to 4.4); and predicted maximal oxygen uptake (OR 2.0, 95% CI 1.0 to 4.3). A clinical rule for predicting the development of postoperative pulmonary complications predicted 82% of participants who developed complications. The odds of high risk participants developing pulmonary complications were 8.4 (95% CI 3.3 to 21.3) times that of low risk participants.

CONCLUSION

This clinical rule for predicting the risk of developing postoperative pulmonary complications from five risk factors may prove useful in prioritising postoperative respiratory physiotherapy. Further research is needed to validate the rule.

摘要

问题

上腹部手术后发生术后肺部并发症的风险能否被预测?

设计

前瞻性观察研究。

参与者

268例连续接受择期上腹部手术的患者,他们在术前和术后均接受了标准化的预防性呼吸物理治疗。

观察指标

预测因素为17项术前和术中风险因素。当出现以下四项或更多标准时,诊断为术后肺部并发症:肺不张/实变的影像学证据、体温>38摄氏度、氧合血红蛋白饱和度<90%、异常痰液产生、痰培养提示感染、白细胞计数升高、听诊异常发现或医生诊断为肺部并发症。

结果

35名参与者(13%)发生了术后肺部并发症。五项风险因素可预测术后肺部并发症:麻醉持续时间(比值比4.3,95%置信区间1.7至10.8);手术类别(比值比2.3,95%置信区间1.1至4.7);当前吸烟(比值比2.1,95%置信区间1.0至4.5);呼吸系统合并症(比值比2.1,95%置信区间1.0至4.4);以及预测的最大摄氧量(比值比2.0,95%置信区间1.0至4.3)。一项预测术后肺部并发症发生的临床规则可预测82%发生并发症的参与者。高风险参与者发生肺部并发症的几率是低风险参与者的8.4(95%置信区间3.3至21.3)倍。

结论

这项由五项风险因素预测术后肺部并发症风险的临床规则可能有助于确定术后呼吸物理治疗的优先顺序。需要进一步研究来验证该规则。

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