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用于治疗乳腺癌和妇科癌症肝转移的局部区域疗法。

Locoregional Therapies for the Treatment of Hepatic Metastases from Breast and Gynecologic Cancers.

作者信息

Mouli Samdeep K, Gupta Ramona, Sheth Neil, Gordon Andrew C, Lewandowski Robert J

机构信息

Section of Interventional Radiology, Department of Radiology, Northwestern University, Chicago, Illinois.

Division of Hematology and Oncology, Department of Medicine, Northwestern University, Chicago, Illinois.

出版信息

Semin Intervent Radiol. 2018 Mar;35(1):29-34. doi: 10.1055/s-0038-1636518. Epub 2018 Apr 5.

DOI:10.1055/s-0038-1636518
PMID:29628613
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5886768/
Abstract

Breast cancer is the most common women's malignancy in the United States and is the second leading cause of cancer death. More than half of patients with breast cancer will develop hepatic metastases; this portends a poorer prognosis. In the appropriately selected patient, there does appear to be a role for curative (surgery, ablation) or palliative (intra-arterial treatments) locoregional therapy. Gynecologic malignancies are less common and metastases to the liver are most often seen in the setting of disseminated disease. The role of locoregional therapies in these patients is not well reported. The purpose of this article is to review the outcomes data of locoregional therapies in the treatment of hepatic metastases from breast and gynecologic malignancies.

摘要

乳腺癌是美国女性中最常见的恶性肿瘤,也是癌症死亡的第二大主要原因。超过一半的乳腺癌患者会发生肝转移;这预示着预后较差。在适当选择的患者中,根治性(手术、消融)或姑息性(动脉内治疗)局部区域治疗似乎确实有作用。妇科恶性肿瘤不太常见,肝转移最常出现在播散性疾病的情况下。局部区域治疗在这些患者中的作用报道较少。本文的目的是回顾局部区域治疗在乳腺癌和妇科恶性肿瘤肝转移治疗中的疗效数据。

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本文引用的文献

1
NCCN Guidelines Insights: Breast Cancer, Version 1.2017.NCCN 指南解读:乳腺癌,第 1.2017 版。
J Natl Compr Canc Netw. 2017 Apr;15(4):433-451. doi: 10.6004/jnccn.2017.0044.
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Liver Metastases From Breast Cancer: What Role for Surgery? Indications and Results.乳腺癌肝转移:手术的作用是什么?适应证与结果
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Cardiovasc Intervent Radiol. 2017 Jan;40(1):81-89. doi: 10.1007/s00270-016-1465-4. Epub 2016 Sep 19.
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Yttrium-90 Radioembolization for Breast Cancer Liver Metastases.钇-90放射性栓塞治疗乳腺癌肝转移
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6
Yttrium-90 Radioembolization of Advanced, Unresectable Breast Cancer Liver Metastases-A Single-Center Experience.钇-90放射性栓塞治疗晚期不可切除乳腺癌肝转移——单中心经验
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Safety, Efficacy, and Prognostic Factors After Radioembolization of Hepatic Metastases from Breast Cancer: A Large Single-Center Experience in 81 Patients.乳腺癌肝转移放射性栓塞治疗的安全性、疗效和预后因素:81 例大型单中心经验。
J Nucl Med. 2016 Apr;57(4):517-23. doi: 10.2967/jnumed.115.165050. Epub 2016 Jan 7.
8
Yttrium-90 radioembolization stops progression of targeted breast cancer liver metastases after failed chemotherapy.在化疗失败后,钇-90放射性栓塞可阻止靶向性乳腺癌肝转移的进展。
J Vasc Interv Radiol. 2014 Oct;25(10):1523-32, 1532.e1-2. doi: 10.1016/j.jvir.2014.07.007. Epub 2014 Aug 22.
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Hepatogastroenterology. 2014 Jan-Feb;61(129):181-6.
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Int J Radiat Oncol Biol Phys. 2014 Apr 1;88(5):1025-31. doi: 10.1016/j.ijrobp.2013.12.040.