Tsitskari Maria, Filippiadis Dimitris, Kostantos Chrysostomos, Palialexis Kostantinos, Zavridis Periklis, Kelekis Nikolaos, Brountzos Elias
Second Department of Radiology, Unit of Vascular and Interventional Radiology, Attikon University Hospital, National and Kapodistrian University of Athens, Greece.
Ann Gastroenterol. 2019 Mar-Apr;32(2):147-155. doi: 10.20524/aog.2018.0338. Epub 2018 Dec 14.
Colorectal cancer is a leading cause of death both in Europe and worldwide. Unfortunately, 20-25% of patients with colorectal cancer already have metastases at the time of diagnosis, while 50-60% of the remainder will develop metastases later during the course of the disease. Although hepatic excision is the first-line treatment for patients with liver-limited colorectal metastases and is reported to prolong the survival of these patients, few patients are candidates. Locoregional therapy encompasses minimally invasive techniques practiced by interventional radiology. Most widely used locoregional therapies include ablative treatments (radiofrequency ablation, microwave ablation) and transcatheter intra-arterial therapies (transarterial chemoembolization, and radioembolization with yttrium-90).
结直肠癌是欧洲和全球主要的死亡原因之一。不幸的是，20%至25%的结直肠癌患者在诊断时就已经发生了转移，而其余患者中有50%至60%会在疾病过程中随后发生转移。尽管肝切除是肝局限性结直肠癌转移患者的一线治疗方法，并且据报道可延长这些患者的生存期，但符合条件的患者很少。局部区域治疗包括介入放射学所采用的微创技术。最常用的局部区域治疗方法包括消融治疗（射频消融、微波消融）和经导管动脉内治疗（经动脉化疗栓塞以及钇-90放射性栓塞）。
