Kalra Sanjay, Kalra Bharti
Department of Endocrinology, Bharti Hospital, Karnal, Haryana, India.
Department of Obstetrics, Bharti Hospital, Karnal, Haryana, India.
J Midlife Health. 2018 Jan-Mar;9(1):36-38. doi: 10.4103/jmh.JMH_52_16.
This review describes the mechanistic, animal, and clinical data related to the use of inositols in midlife. It covers studies related to the mechanism of action of myo-inositol and D-chiro-inositol and randomized controlled trials conducted in postmenopausal women with metabolic syndrome and supports these data with the results of and animal studies on inositol in nephropathy and other related conditions. Recent advances related to biochemistry, pharmaceutical science, and genetics are discussed. It concludes that inositols have a potential role to play in maintaining metabolic health in postmenopausal women.
本综述描述了与中年期使用肌醇相关的机制、动物和临床数据。它涵盖了与肌醇和D-手性肌醇作用机制相关的研究，以及在患有代谢综合征的绝经后妇女中进行的随机对照试验，并用关于肌醇在肾病及其他相关病症中的人体和动物研究结果来支持这些数据。文中还讨论了生物化学、制药科学和遗传学方面的最新进展。结论是，肌醇在维持绝经后妇女的代谢健康方面可能发挥作用。
