Kalra Bharti, Kalra Sanjay, Sharma J B
Department of Obstetrics, Bharti Hospital, Karnal, Haryana, India.
Department of Endocrinology, Bharti Hospital, Karnal, Haryana, India.
Indian J Endocrinol Metab. 2016 Sep-Oct;20(5):720-724. doi: 10.4103/2230-8210.189231.
This review describes the rationale, biochemical, and clinical data related to the use of inositols in polycystic ovary syndrome (PCOS). It covers studies related to the mechanism of action of myo-inositol and D-chiro-inositol (MDI), with randomized controlled trials conducted in women with PCOS, and utilizes these data to suggest pragmatic indications and methods for using MDI combination in PCOS. Rationally crafted inositol combinations have a potential role to play in maintaining metabolic, endocrine, and reproductive health in women with PCOS.
本综述描述了与多囊卵巢综合征（PCOS）中使用肌醇相关的理论基础、生化和临床数据。它涵盖了与肌醇和D-手性肌醇（MDI）作用机制相关的研究，这些研究是在PCOS女性中进行的随机对照试验，并利用这些数据提出了在PCOS中使用MDI组合的实用适应症和方法。合理设计的肌醇组合在维持PCOS女性的代谢、内分泌和生殖健康方面可能发挥作用。
