Medaglia Alice Annalisa, Marco-Hernández Javier, de Ossó Acuña José Tomás, Hermida Lama Evelyn, Martínez-Rebollar María, Caballero Miguel, Rodríguez-Carunchio Leonardo, García Felipe
1 Infectious Diseases Department, Hospital Clinic de Barcelona, Hospital Clinic de Barcelona, Barcelona, Spain.
2 Otorhinolaryngology Department, Hospital Clínic de Barcelona, Barcelona, Spain.
Int J STD AIDS. 2018 Sep;29(10):1039-1042. doi: 10.1177/0956462418761259. Epub 2018 Apr 8.
Fusarium infections are very rare in HIV-infected patients, even in patients in advanced stages of immunosuppression. All the reported cases in the literature are of disseminated infection, and with poor outcomes despite prompt and appropriate treatment. To the best of our knowledge, this is the first report of a localized infection with Fusarium keratoplasticum in an HIV-positive patient, successfully treated with a combination of antifungal therapy and surgical removal of the focus.
镰刀菌感染在HIV感染患者中非常罕见,即使在免疫抑制晚期的患者中也是如此。文献中报道的所有病例均为播散性感染,尽管及时给予了恰当治疗,但预后不佳。据我们所知,这是首例关于HIV阳性患者发生局限型角膜镰刀菌感染的报告,通过抗真菌治疗联合病灶手术切除成功治愈。