Günes Mehmet Emin
Ann Ital Chir. 2018;89:30-35.
We aimed to compare the tru-cut biopsy and postoperative pathology results of breast lesions with suspicion of malignancy. Furthermore we aimed to determine the efficacy, specificity and sensitivity of the tru-cut biopsy.
140 patients who were operated due to breast mass following tru-cut biopsy were retrospectively evaluated. Patients' demographic characteristics, imaging findings, biopsy and histopathology results were compared.
The mean age of 140 patients was 51.3 (Ranged: 17-83 ages). Malignancy was statistically more common in patients older than 45 years old. According to tru-cut biopsy results 103 (73.5%) lesions were malign, 32 (23%) benign, and 5 (3,5%) suspicious. Histopathological evaluation established 113 (% 80.7) malign and 27 (19,3%) benign lesions. Tru-cut biopsy had a sensitivity, specifity, positive predictive value, negative predictive value and diagnostic accuracy of 93.5%, 95.4%, 99%, 75% and 80%, respectively in this study.
Our findings have confirmed that tru-cut biopsy is an accurate, reliable and as effective as open surgery for breast cancer diagnosis. The higher success rates may achieve by accordance of triple assessment which includes clinical, radiological and pathological evaluation with tru-cut biopsy.
Breast cancer, Core needle biopsy, Preoperative evaluation, Tru-cut biops.
我们旨在比较对怀疑为恶性的乳腺病变进行粗针活检与术后病理结果。此外，我们旨在确定粗针活检的有效性、特异性和敏感性。
对140例在粗针活检后因乳腺肿块接受手术的患者进行回顾性评估。比较患者的人口统计学特征、影像学表现、活检及组织病理学结果。
140例患者的平均年龄为51.3岁（范围：17 - 83岁）。统计学上，45岁以上患者中恶性病变更为常见。根据粗针活检结果，103例（73.5%）病变为恶性，32例（23%）为良性，5例（3.5%）为可疑。组织病理学评估确定113例（80.7%）为恶性病变，27例（19.3%）为良性病变。在本研究中，粗针活检的敏感性、特异性、阳性预测值、阴性预测值和诊断准确性分别为93.5%、95.4%、99%、75%和80%。
我们的研究结果证实，粗针活检对于乳腺癌诊断是准确、可靠且与开放手术同样有效的。通过将包括临床、放射学和病理学评估在内的三重评估与粗针活检相结合，可能会获得更高的成功率。
乳腺癌；粗针活检；术前评估；粗针活检
