Ekinci Özgür
Department of Medical Pathology, Gazi University Faculty of Medicine, ANKARA, TURKEY.
Turk Patoloji Derg. 2018;34(3):242-246. doi: 10.5146/tjpath.2018.01426.
The aim of this study was to review our series of pancreatic resection specimen handling results and focus on the positivity of the tumor in various retroperitoneal surgical margins.
Our archival cases from 2008 to 2018 were retrospectively examined, especially for the surgical margins. The demographics, tumor locations, and the diagnoses were recorded. The state of all of the retropancreatic surgical margins (anterior, posterior, superior, inferior, superior mesenteric vein and artery) were recorded.
There were 285 cases, of which 157 were male and 128 female. The mean and median ages were 63.3 and 64, respectively. Invasive ductal adenocarcinoma was the most common diagnosis [202 cases (70.8%)]. Positivity was observed in 90 (31.5%) margins. The majority was in the superior mesenteric vein margin [n:24 (8.4%)]. This was followed by the anterior, resection and SMA margins.
Pancreatic resections should macroscopically be sampled by recommended methods in order to detect positivity in individual margins by proper grossing techniques. When this is applied, the superior mesenteric vein margin is the margin most prone to be positive for the tumor.
本研究旨在回顾我们一系列胰腺切除标本的处理结果，并重点关注肿瘤在各个腹膜后手术切缘的阳性情况。
对我们2008年至2018年的存档病例进行回顾性检查，尤其关注手术切缘。记录人口统计学数据、肿瘤位置和诊断结果。记录所有胰后手术切缘（前、后、上、下、肠系膜上静脉和动脉）的情况。
共有285例病例，其中男性157例，女性128例。平均年龄和中位数年龄分别为63.3岁和64岁。浸润性导管腺癌是最常见的诊断[202例（70.8%）]。90个（31.5%）切缘观察到阳性。大多数位于肠系膜上静脉切缘[n：24（8.4%）]。其次是前切缘、切除切缘和肠系膜上动脉切缘。
胰腺切除术应采用推荐方法进行宏观取材，以便通过适当的大体标本制作技术检测各个切缘的阳性情况。应用此方法时，肠系膜上静脉切缘是肿瘤最易出现阳性的切缘。
