Manyak M J, Russo A, Smith P D, Glatstein E
National Cancer Institute, Radiation Oncology Branch, Bethesda, MD 20892.
J Clin Oncol. 1988 Feb;6(2):380-91. doi: 10.1200/JCO.1988.6.2.380.
Photodynamic therapy (PDT) is an experimental cancer treatment modality that selectively destroys cancer cells by an interaction between absorbed light and a retained photosensitizing agent. This review discusses the basic components of photodynamic activity and examines the clinical applications of photodynamic therapy in cancer treatment. Treatment of superficial and early-stage malignancies is encouraging. Technologic advancement and further elucidation of the fundamental basis of photodynamic action should permit treatment of more advanced malignancies.
光动力疗法（PDT）是一种实验性癌症治疗方式，通过吸收的光与保留的光敏剂之间的相互作用选择性地破坏癌细胞。本综述讨论了光动力活性的基本组成部分，并研究了光动力疗法在癌症治疗中的临床应用。浅表和早期恶性肿瘤的治疗效果令人鼓舞。技术进步以及对光动力作用基本原理的进一步阐明应能使更晚期恶性肿瘤的治疗成为可能。
