Department of Psychological Sciences, Birkbeck, University of London, London, UK.
Psychooncology. 2018 Jul;27(7):1780-1786. doi: 10.1002/pon.4727. Epub 2018 May 11.
Breast cancer enhances anxiety and depressive vulnerability, profoundly impairing the quality of life in survivors. Hinging on recent research that training attentional control can reduce emotional vulnerability, we assess how improving cognitive function could reduce emotional vulnerability in female survivors of breast cancer.
Participants took part in a course of adaptive dual n-back cognitive training (Training Group) or a non-adaptive active control group (Active Control) for 12 days across a 2-week period. Transfer-related training gains were assessed immediately after the intervention, at a shorter 1-month follow-up and at a longer follow-up time of approximately 15 months post intervention, to assess sustainability of training effects.
Adaptive cognitive training reduced anxiety and rumination with effects evident at shorter and longer term follow-up assessments.
Our results are among the first to suggest that adaptive cognitive training can reduce emotional vulnerability in breast cancer, with the potential to enhance quality of life in survivorship. Our findings have profound implications for designing interventions targeting cognitive function in populations who have suffered from cancer.
乳腺癌会增加焦虑和抑郁的易感性，极大地降低幸存者的生活质量。鉴于最近的研究表明，训练注意力控制可以降低情绪脆弱性，我们评估了改善认知功能如何降低乳腺癌女性幸存者的情绪脆弱性。
参与者参加了为期两周的 12 天适应性双 n 回认知训练课程（训练组）或非适应性主动对照组（主动对照组）。干预后立即、干预后 1 个月短期随访和大约 15 个月的长期随访评估转移相关训练增益，以评估训练效果的可持续性。
适应性认知训练可降低焦虑和反刍，短期和长期随访评估均可见效果。
我们的研究结果是首次表明适应性认知训练可以降低乳腺癌患者的情绪脆弱性，有潜力提高生存者的生活质量。我们的研究结果对针对癌症患者的认知功能干预设计具有深远意义。
