小鼠c-fms原癌基因的遗传定位至第18号染色体。
Genetic mapping of the mouse c-fms proto-oncogene to chromosome 18.
作者信息
Hoggan M D, Halden N F, Buckler C E, Kozak C A
机构信息
Laboratory of Molecular Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland 20892.
出版信息
J Virol. 1988 Mar;62(3):1055-6. doi: 10.1128/JVI.62.3.1055-1056.1988.
Abstract
Chinese hamster X mouse somatic cell hybrids were analyzed by Southern blot hybridization with a probe specific for the cellular c-fms proto-oncogene. Results demonstrate that Fms, the genetic locus containing this sequence, maps to mouse chromosome 18. Mouse Fms is thus not linked to the same set of genes involved in growth regulation that human FMS is linked to.
摘要
用针对细胞c-fms原癌基因的特异性探针，通过Southern印迹杂交分析了中国仓鼠与小鼠的体细胞杂种。结果表明，包含该序列的基因座Fms定位于小鼠18号染色体。因此，小鼠Fms与人类FMS所关联的参与生长调节的同一组基因没有连锁关系。
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