Li S Z, Oikawa T, Yoshida M C, Naito H, Kuzumaki N
Laboratory of Molecular Genetics, Hokkaido University School of Medicine, Sapporo, Japan.
Cytogenet Cell Genet. 1989;52(1-2):42-4. doi: 10.1159/000132836.
Using a panel of rat x mouse somatic cell hybrids and in situ hybridization, we determined the chromosomal location of the rat FOS gene locus. Southern blot analysis assigned this oncogene to rat chromosome 6. In situ hybridization confirmed this finding and mapped the gene more precisely to 6q21----q2.
利用一组大鼠×小鼠体细胞杂种和原位杂交技术,我们确定了大鼠FOS基因位点的染色体定位。Southern印迹分析将这个癌基因定位于大鼠的6号染色体。原位杂交证实了这一发现,并将该基因更精确地定位于6q21----q2。