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颈动脉内膜切除术后出现的血流紊乱:残余及复发性颈动脉狭窄的先兆。

Turbulence occurring after carotid bifurcation endarterectomy: a harbinger of residual and recurrent carotid stenosis.

作者信息

Bandyk D F, Kaebnick H W, Adams M B, Towne J B

机构信息

Department of Surgery, Medical College of Wisconsin, Milwaukee.

出版信息

J Vasc Surg. 1988 Feb;7(2):261-74. doi: 10.1067/mva.1988.avs0070261.

Abstract

The goal of carotid endarterectomy is to remove an obstructing or embologenic lesion and reconstruct a durable arterial segment free of flow abnormality. The technical adequacy of 250 endarterectomy sites in 235 patients was assessed at operation by pulsed Doppler spectral analysis and arteriography and was correlated with postoperative patency, the incidence of residual and recurrent stenosis, and clinical outcome. Duplex scanning was used after operation to categorize disease severity. At operation, 10 patients (4%) had angiographic and Doppler flow abnormalities identified in the internal carotid artery. Vessel exploration identified intimal flaps, platelet aggregation, or stricture. Residual flow disturbances at the endarterectomy site correlated with perioperative thrombosis and stroke, angiographic abnormalities, primary closure of the arteriotomy, and a postoperative duplex scan consistent with stenosis. In 175 patients (182 sites) with normal arterial flow after carotid bifurcation endarterectomy, no thrombotic events occurred and the incidence of recurrent stenosis (life-table analysis) was zero at 3 months, 5% at 1 year, and 9% at 2 years. The incidence of occlusion and recurrent stenosis was increased (8% at 3 months, 18% at 1 year, and 21% at 2 years) in 68 arteries with residual flow disturbance identified at operation. Assessment of endarterectomy sites for turbulence identifies anatomic lesions that threaten patency and increase the incidence of residual and recurrent stenosis.

摘要

颈动脉内膜切除术的目标是切除阻塞性或致栓性病变,并重建一个没有血流异常的持久动脉段。通过脉冲多普勒频谱分析和动脉造影对235例患者的250个内膜切除部位的技术充分性在手术时进行评估,并将其与术后通畅情况、残余和复发性狭窄的发生率以及临床结果相关联。术后使用双功扫描对疾病严重程度进行分类。手术时,10例患者(4%)在内颈动脉中发现了血管造影和多普勒血流异常。血管探查发现了内膜瓣、血小板聚集或狭窄。内膜切除部位的残余血流紊乱与围手术期血栓形成和中风、血管造影异常、动脉切开术的一期缝合以及与狭窄一致的术后双功扫描相关。在175例(182个部位)颈动脉分叉内膜切除术后动脉血流正常的患者中,未发生血栓事件,复发性狭窄的发生率(寿命表分析)在3个月时为零,1年时为5%,2年时为9%。在手术时发现有残余血流紊乱的68条动脉中,闭塞和复发性狭窄的发生率增加(3个月时为8%,1年时为18%,2年时为21%)。对内膜切除部位的血流紊乱进行评估可识别出威胁通畅性并增加残余和复发性狭窄发生率的解剖病变。

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