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比较 Ahmed 和 Baerveldt 青光眼引流阀与白内障联合摘出术。

Comparison of the Ahmed and Baerveldt glaucoma shunts with combined cataract extraction.

机构信息

Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ont.

Department of Ophthalmology, Barzilai University Hospital, Ashkelon, Israel.

出版信息

Can J Ophthalmol. 2018 Apr;53(2):124-130. doi: 10.1016/j.jcjo.2017.08.017. Epub 2017 Nov 27.

Abstract

OBJECTIVE

To compare the surgical outcomes of combined phacoemulsification with either Ahmed glaucoma valve (AGV) or Baerveldt glaucoma implant (BGI).

DESIGN

Retrospective cohort study.

PARTICIPANTS

A total of 104 eyes that underwent combined phacoemulsification with either AGV (PhacoAGV; n = 57) or BGI (PhacoBGI; n = 47) implantation.

METHODS

Failure was defined as uncontrolled intraocular pressure (IOP; <5 mm Hg, ≥18 mm Hg, or <20% reduction), additional glaucoma surgery, vision-threatening complications, or progression to no-light-perception vision.

RESULTS

The PhacoAGV group was older (p = 0.03), had poorer baseline visual acuity (VA; p = 0.001), and had fewer previous glaucoma surgeries (p = 0.04). Both groups had similar baseline IOP (PhacoAGV: 26.4 ± 8.3 mm Hg; PhacoBGI: 25.7 ± 7.3; p = 0.66) and glaucoma medications (PhacoAGV: 3.8 ± 1.0; PhacoBGI: 3.6 ± 1.5; p = 0.54). At 2 years, failure rates were 44% in the PhacoAGV group and 23% in the PhacoBGI group (p = 0.02). Both groups had similar mean IOP reduction (PhacoAGV: 45%; PhacoBGI: 47%, p = 0.67) and medication use reduction (PhacoAGV: 47%; PhacoBGI: 58%, p = 0.38). The PhacoBGI group had higher IOP and medication use up to 1 month (p < 0.05). Both groups improved in VA from baseline (p < 0.05) and had similar overall complication rates (p = 0.31). The PhacoBGI group required more overall interventions (p < 0.0005).

CONCLUSIONS

This comparative study found no difference in IOP, glaucoma medications, or complication rates between PhacoAGV and PhacoBGI at 2 years, despite BGIs being implanted in patients at higher risk for failure. The PhacoAGV group had higher failure rates at 2 years. Both groups had significant improvements in VA due to removal of their cataracts. The PhacoBGI group required more interventions, but most of these were minor slit-lamp procedures.

摘要

目的

比较白内障超声乳化联合 Ahmed 青光眼阀(AGV)或 Baerveldt 青光眼植入物(BGI)治疗的手术效果。

设计

回顾性队列研究。

参与者

共 104 只眼接受白内障超声乳化联合 AGV(PhacoAGV;n = 57)或 BGI(PhacoBGI;n = 47)植入术。

方法

失败定义为眼压控制不良(<5mmHg、≥18mmHg 或降低<20%)、需要额外的青光眼手术、出现威胁视力的并发症或视力进展至无光感。

结果

PhacoAGV 组年龄较大(p = 0.03),基线视力(VA;p = 0.001)较差,且既往青光眼手术较少(p = 0.04)。两组基线眼压(PhacoAGV:26.4 ± 8.3mmHg;PhacoBGI:25.7 ± 7.3mmHg;p = 0.66)和青光眼药物使用(PhacoAGV:3.8 ± 1.0;PhacoBGI:3.6 ± 1.5;p = 0.54)相似。2 年时,PhacoAGV 组失败率为 44%,PhacoBGI 组为 23%(p = 0.02)。两组眼压平均降低率(PhacoAGV:45%;PhacoBGI:47%,p = 0.67)和药物使用减少率(PhacoAGV:47%;PhacoBGI:58%,p = 0.38)相似。PhacoBGI 组术后 1 个月内眼压和药物使用更高(p < 0.05)。两组 VA 均从基线改善(p < 0.05),总体并发症发生率相似(p = 0.31)。PhacoBGI 组需要更多的总体干预(p < 0.0005)。

结论

尽管 BGI 植入于失败风险较高的患者,但本比较研究发现,PhacoAGV 和 PhacoBGI 在 2 年时眼压、青光眼药物或并发症发生率无差异。PhacoAGV 组 2 年时失败率较高。两组因白内障摘除均有显著的 VA 改善。PhacoBGI 组需要更多的干预,但大多数是轻微的裂隙灯检查。

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