Vivas Maria, Charréu José, Pombo Bruno, Costa Tomás, Lopes Ana Sofia, Vaz Fernando Trancoso, Santos Maria João, Prieto Isabel
Ophtalmology Department, Hospital Professor Doutor Fernando Fonseca, 2700 Lisbon, Portugal.
Glaucoma Department, Hospital Professor Doutor Fernando Fonseca, 2700 Lisbon, Portugal.
Vision (Basel). 2025 Aug 4;9(3):68. doi: 10.3390/vision9030068.
Combined trabeculectomy-phacoemulsification is known to provoke more inflammation and yield a poorer long-term efficacy than trabeculectomy alone. This study evaluates whether a similar trend exists for Ahmed glaucoma valve implantation when performed with or without concurrent phacoemulsification. We retrospectively analyzed 51 eyes from patients who underwent either Ahmed-Alone (n = 25) or PhacoAhmed (n = 26) surgery over a 5-year period. The primary outcomes included intraocular pressure (IOP), the use of IOP-lowering medications, and the need for further surgical intervention. Absolute success was defined as IOP reduction > 20% and IOP < 21 mmHg without medication; relative success allowed for continued pharmacologic therapy. Both groups showed a significant IOP reduction, with similar final mean IOP values (Ahmed-Alone: 14.02 ± 4.76 mmHg; PhacoAhmed: 13.89 ± 4.17 mmHg; = 0.99) and comparable reductions in medication use ( = 0.52). Reinterventions occurred less frequently and later in the PhacoAhmed group (12% vs. 27.3%; median time: 27.1 vs. 12 months). Absolute success was not achieved in any PhacoAhmed case but occurred in 9.3% of Ahmed-Alone cases; relative success rates were similar (83.3% vs. 81.4%; = 0.291). These findings suggest that combining phacoemulsification with Ahmed valve implantation does not significantly alter efficacy or safety profiles. Additional prospective studies are warranted to assess long-term outcomes.
已知小梁切除术联合白内障超声乳化吸出术比单纯小梁切除术会引发更多炎症且长期疗效更差。本研究评估在进行艾哈迈德青光眼引流阀植入术时,同时进行或不进行白内障超声乳化吸出术是否存在类似趋势。我们回顾性分析了51例患者的51只眼,这些患者在5年期间接受了单纯艾哈迈德手术(n = 25)或白内障超声乳化吸出术联合艾哈迈德手术(n = 26)。主要结局包括眼压(IOP)、降眼压药物的使用以及进一步手术干预的必要性。绝对成功定义为眼压降低>20%且眼压<21 mmHg且无需使用药物;相对成功允许继续进行药物治疗。两组眼压均显著降低,最终平均眼压值相似(单纯艾哈迈德手术组:14.02±4.76 mmHg;白内障超声乳化吸出术联合艾哈迈德手术组:13.89±4.17 mmHg;P = 0.99),药物使用减少情况相当(P = 0.52)。白内障超声乳化吸出术联合艾哈迈德手术组再次干预的频率较低且时间较晚(12%对27.3%;中位时间:27.1个月对12个月)。白内障超声乳化吸出术联合艾哈迈德手术组未出现任何绝对成功的病例,但单纯艾哈迈德手术组有9.3%的病例实现了绝对成功;相对成功率相似(83.3%对81.4%;P = 0.291)。这些发现表明,白内障超声乳化吸出术与艾哈迈德引流阀植入术联合应用不会显著改变疗效或安全性。需要进行更多前瞻性研究来评估长期结局。