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中枢和外周β-内啡肽对经皮电神经刺激的反应。

Central and peripheral beta-endorphin response to transcutaneous electrical nerve stimulation.

作者信息

Facchinetti F, Sforza G, Amidei M, Cozza C, Petraglia F, Montanari C, Genazzani A R

机构信息

Department of Obstetrics and Gynecology, University of Modena, Italy.

出版信息

NIDA Res Monogr. 1986;75:555-8.

PMID:2963222
Abstract

The effects of transcutaneous electrical nerve stimulation on plasma and cerebrospinal fluid (CSF) levels of beta-Endorphin (beta-EP) were studied in 6 groups of pain-free patients. Different modes of TENS were applied for 20 minutes. Regardless of mode and/or frequency of the stimulation plasma and/or CSF beta-EP levels were significantly increased. Plasma and CSF responses were not correlated suggesting that TENS activates different opiatergic pathways at central and peripheral level.

摘要

在6组无痛患者中研究了经皮电刺激神经(TENS)对血浆和脑脊液(CSF)中β-内啡肽(β-EP)水平的影响。采用不同模式的TENS进行20分钟。无论刺激的模式和/或频率如何,血浆和/或脑脊液β-EP水平均显著升高。血浆和脑脊液的反应不相关,这表明TENS在中枢和外周水平激活了不同的阿片能通路。

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