Sorisky Alexander
Chronic Disease Program, Ottawa Hospital Research Institute, Ottawa, Ontario, Canada.
Eur Endocrinol. 2016 Aug;12(2):96-98. doi: 10.17925/EE.2016.12.02.96. Epub 2016 Aug 28.
Subclinical hypothyroidism (SH) is a common condition, with prevalence estimates ranging from 4-20%, depending on the population demographics. Although epidemiological analysis associates it with an increased risk of cardiovascular disease, clinical practice guidelines express uncertainty about whether to monitor or to treat. As we await large-scale, well-designed randomised clinical trials regarding treatment of SH, a review of pathophysiological considerations may be informative to better understand this disorder.
亚临床甲状腺功能减退（SH）是一种常见病症，根据人群统计学特征，其患病率估计在4%至20%之间。尽管流行病学分析将其与心血管疾病风险增加相关联，但临床实践指南对于是否进行监测或治疗仍存在不确定性。在我们等待关于SH治疗的大规模、设计良好的随机临床试验之际，对病理生理学因素进行综述可能有助于更好地理解这种疾病。
