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临床医生对长期阿片类药物治疗停药后非阿片类疼痛治疗的转介因停药原因而异。

Clinician Referrals for Non-opioid Pain Care Following Discontinuation of Long-term Opioid Therapy Differ Based on Reasons for Discontinuation.

机构信息

Center to Improve Veteran Involvement in Care,, VA Portland Health Care System, Portland, OR, USA.

Department of Psychiatry, Oregon Health and Science University, Portland, OR, USA.

出版信息

J Gen Intern Med. 2018 May;33(Suppl 1):24-30. doi: 10.1007/s11606-018-4329-6.

Abstract

BACKGROUND

Little is known about pain care offered to patients discontinued from long-term opioid therapy (LTOT) by their prescriber due to aberrant behaviors versus other reasons.

OBJECTIVE

This study aimed to compare rates of non-opioid analgesic pharmacotherapy initiation and clinician referrals for non-pharmacologic pain treatment, complementary and integrative pain therapies, and specialty mental health and substance use disorder treatment between patients discontinued from opioid therapy due to aberrant behaviors versus other reasons.

DESIGN

The design included retrospective manual electronic health record review and administrative data abstraction.

PARTICIPANTS

Patients were sampled from a national cohort of US Department of Veterans Affairs patients prescribed continuous opioid therapy in 2011 who subsequently discontinued opioid therapy in 2012. The study sample comprised 509 patients discontinued from LTOT by opioid-prescribing clinicians.

MAIN MEASURES

The primary independent variable was reason for discontinuation of LTOT (aberrant behaviors versus other reasons). Pain care dichotomous outcomes included clinician use of an opioid taper; initiating new non-opioid analgesic pharmacotherapy; and referrals for non-pharmacologic pain treatment, complementary and integrative pain therapies, and specialty mental health and substance use disorder treatment.

KEY RESULTS

We observed low rates of opioid taper (15% of patients), initiations of new or modifications of existing non-opioid analgesic pharmacotherapy (45% of patients), and clinician referrals for non-pharmacologic pain treatment (58% of patients) and complementary and integrative therapies (25% of patients). Patients discontinued due to aberrant behaviors, relative to patients discontinued for other reasons, were more likely to receive opioid tapers (adjusted OR = 5.60, 95% CI = 2.10-14.93), receive new non-opioid analgesic medications or dose changes to an existing non-opioid analgesic medications (adjusted OR = 2.61, 95% CI = 1.59-4.29), or be referred for specialty substance use disorder treatment (adjusted OR = 7.39, 95% CI = 3.76-14.53).

CONCLUSIONS

These findings highlight the variability in referral rates for different types of non-opioid pain treatments and challenges accessing specific types of pain care.

摘要

背景

对于因异常行为而停止长期阿片类药物治疗(LTOT)的患者,与因其他原因停止 LTOT 的患者相比,我们对其接受的疼痛护理知之甚少。

目的

本研究旨在比较因异常行为与其他原因停止阿片类药物治疗的患者开始非阿片类镇痛药物治疗和临床医生转介非药物性疼痛治疗、补充和整合性疼痛治疗以及专业精神健康和物质使用障碍治疗的比率。

设计

该设计包括回顾性手动电子健康记录审查和行政数据提取。

参与者

从美国退伍军人事务部 2011 年接受连续阿片类药物治疗的全国队列中抽取患者样本,这些患者随后在 2012 年停止阿片类药物治疗。研究样本包括 509 名因异常行为而被开处方的临床医生停止 LTOT 的患者。

主要措施

主要的独立变量是 LTOT 停药的原因(异常行为与其他原因)。疼痛护理的二项结局指标包括临床医生使用阿片类药物递减法;开始新的或修改现有的非阿片类镇痛药物治疗;以及非药物性疼痛治疗、补充和整合性疼痛治疗以及专业精神健康和物质使用障碍治疗的转介。

主要结果

我们观察到阿片类药物递减的比例较低(15%的患者),开始新的或修改现有的非阿片类镇痛药物治疗的比例(45%的患者),以及临床医生转介非药物性疼痛治疗(58%的患者)和补充和整合性治疗(25%的患者)的比例较低。与因其他原因停止 LTOT 的患者相比,因异常行为而停止 LTOT 的患者更有可能接受阿片类药物递减(调整后的比值比 = 5.60,95%置信区间 = 2.10-14.93),接受新的非阿片类镇痛药物或改变现有非阿片类镇痛药物的剂量(调整后的比值比 = 2.61,95%置信区间 = 1.59-4.29),或接受专业物质使用障碍治疗的转介(调整后的比值比 = 7.39,95%置信区间 = 3.76-14.53)。

结论

这些发现突出了不同类型非阿片类疼痛治疗转介率的差异,以及获得特定类型疼痛治疗的挑战。

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本文引用的文献

2
Secular trends in opioid prescribing in the USA.美国阿片类药物处方的长期趋势。
J Pain Res. 2017 Feb 14;10:383-387. doi: 10.2147/JPR.S129553. eCollection 2017.

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