Center of Innovation for Veteran-Centered and Value-Driven Care, VA Eastern Colorado Health Care System, Denver, CO, USA.
Pain Research, Informatics, Multimorbidities and Education (PRIME) Center of Innovation, VA Connecticut Healthcare System, West Haven, CT, USA.
J Gen Intern Med. 2018 May;33(Suppl 1):38-45. doi: 10.1007/s11606-018-4324-y.
Expert guidelines recommend non-pharmacologic treatments and non-opioid medications for chronic pain and recommend against initiating long-term opioid therapy (LTOT).
We examined whether veterans with incident chronic pain receiving care at facilities with greater utilization of non-pharmacologic treatments and non-opioid medications are less likely to initiate LTOT.
Retrospective cohort study PARTICIPANTS: Veterans receiving primary care from a Veterans Health Administration facility with incident chronic pain between 1/1/2010 and 12/31/2015 based on either of 2 criteria: (1) persistent moderate-to-severe patient-reported pain and (2) diagnoses "likely to represent" chronic pain.
The independent variable was facility-level utilization of pain-related treatment modalities (non-pharmacologic, non-opioid medications, LTOT) in the prior calendar year. The dependent variable was patient-level initiation of LTOT (≥ 90 days within 365 days) in the subsequent year, adjusting for patient characteristics.
Among 1,094,569 veterans with incident chronic pain from 2010 to 2015, there was wide facility-level variation in utilization of 10 pain-related treatment modalities, including initiation of LTOT (median, 16%; range, 5-32%). Veterans receiving care at facilities with greater utilization of non-pharmacologic treatments were less likely to initiate LTOT in the year following incident chronic pain. Conversely, veterans receiving care at facilities with greater non-opioid and opioid medication utilization were more likely to initiate LTOT; this association was strongest for past year facility-level LTOT initiation (adjusted rate ratio, 2.10; 95% confidence interval, 2.06-2.15, top vs. bottom quartile of facility-level LTOT initiation in prior calendar year).
Facility-level utilization patterns of non-pharmacologic, non-opioid, and opioid treatments for chronic pain are associated with subsequent patient-level initiation of LTOT among veterans with incident chronic pain. Further studies should seek to understand facility-level variation in chronic pain care and to identify facility-level utilization patterns that are associated with improved patient outcomes.
专家指南建议对慢性疼痛采用非药物治疗和非阿片类药物治疗,并反对启动长期阿片类药物治疗(LTOT)。
我们研究了在非药物治疗和非阿片类药物使用率较高的医疗机构接受治疗的新发慢性疼痛患者是否不太可能开始 LTOT。
回顾性队列研究。
根据以下两项标准之一,2010 年 1 月 1 日至 2015 年 12 月 31 日期间在退伍军人健康管理局(VA)医疗机构接受初级保健的新发慢性疼痛患者:(1)持续的中重度患者报告疼痛和(2)“可能代表”慢性疼痛的诊断。
自变量为前一年中与疼痛相关的治疗模式(非药物、非阿片类药物、LTOT)的设施使用率。因变量为随后一年内患者开始 LTOT(365 天内≥90 天),调整了患者特征。
在 2010 年至 2015 年间的 1094569 名新发慢性疼痛患者中,10 种与疼痛相关的治疗方法的使用率在机构间存在广泛差异,包括 LTOT 的启动(中位数,16%;范围,5-32%)。在接受非药物治疗使用率较高的医疗机构接受治疗的患者不太可能在新发慢性疼痛后一年内开始 LTOT。相反,在接受非阿片类药物和阿片类药物使用率较高的医疗机构接受治疗的患者更有可能开始 LTOT;这种关联在过去一年中机构层面 LTOT 启动率最高(调整后的比率比,2.10;95%置信区间,2.06-2.15,上四分位与下四分位)。
慢性疼痛的非药物、非阿片类和阿片类治疗的机构层面使用模式与新发慢性疼痛患者随后开始 LTOT 相关。进一步的研究应寻求了解慢性疼痛护理的机构间差异,并确定与改善患者结局相关的机构层面使用模式。