• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

老年人2型糖尿病:现代管理关键原则的简要声明,包括衰弱评估。一项全国性利益相关者合作倡议。

Type 2 diabetes mellitus in older people: a brief statement of key principles of modern day management including the assessment of frailty. A national collaborative stakeholder initiative.

作者信息

Strain W D, Hope S V, Green A, Kar P, Valabhji J, Sinclair A J

机构信息

Diabetes and Vascular Research Centre, University of Exeter Medical School, Medical Academic Staff Committee, Lead Physician, Academic Department of Healthcare for the Older Person, Royal Devon and Exeter Hospital Trust, and British Medical Association Medical Academic Staff Committee.

Secretary, British Geriatrics Society Special Interest Group in Diabetes, and University of Exeter Medical School.

出版信息

Diabet Med. 2018 Jul;35(7):838-845. doi: 10.1111/dme.13644. Epub 2018 May 6.

DOI:10.1111/dme.13644
PMID:29633351
Abstract

Rates of population ageing are unprecedented and this, combined with the progressive urbanization of lifestyles, has led to a dramatic shift in the epidemiology of diabetes towards old age, particularly to those aged 60-79 years. Both ageing and diabetes are recognized as important risk factors for the development of functional decline and disability. In addition, diabetes is associated with a high economic, social and health burden. Traditional macrovascular and microvascular complications of diabetes appear to account for less than half of the diabetes-related disability observed in older people. Despite this, older adults are under-represented in clinical trials. Guidelines from organizations such as the National Institute for Health and Care Excellence (NICE), the European Association for the Study of Diabetes, and the American Diabetes Association acknowledge the need for individualized care, but the glycaemic targets that are suggested to constitute good control [HbA 53-59 mmol/mol (7-7.5%)] are too tight for frail older individuals. We present a framework for the assessment of older adults and guidelines for the management of this population according to their frailty status, with the intention of reducing complications and improving quality of life for these people.

摘要

人口老龄化速度空前,再加上生活方式的逐步城市化,导致糖尿病流行病学发生了巨大转变,发病年龄趋于老年化,尤其是60 - 79岁人群。老龄化和糖尿病都被认为是功能衰退和残疾发展的重要风险因素。此外,糖尿病还伴随着高昂的经济、社会和健康负担。糖尿病传统的大血管和微血管并发症似乎只占老年人中观察到的与糖尿病相关残疾的不到一半。尽管如此,老年人在临床试验中的代表性不足。英国国家卫生与临床优化研究所(NICE)、欧洲糖尿病研究协会和美国糖尿病协会等组织的指南都承认需要个性化护理,但建议的构成良好控制的血糖目标[糖化血红蛋白53 - 59 mmol/mol(7 - 7.5%)]对体弱的老年人来说过于严格。我们提出了一个评估老年人的框架以及根据其虚弱状况管理这一人群的指南,旨在减少这些人的并发症并提高其生活质量。

相似文献

1
Type 2 diabetes mellitus in older people: a brief statement of key principles of modern day management including the assessment of frailty. A national collaborative stakeholder initiative.老年人2型糖尿病:现代管理关键原则的简要声明,包括衰弱评估。一项全国性利益相关者合作倡议。
Diabet Med. 2018 Jul;35(7):838-845. doi: 10.1111/dme.13644. Epub 2018 May 6.
2
Prognostic Value of Glycated Hemoglobin in Frail Older Diabetic Patients With Hip Fracture.糖化血红蛋白对合并髋部骨折的衰弱老年糖尿病患者的预后价值。
Front Endocrinol (Lausanne). 2021 Nov 18;12:770400. doi: 10.3389/fendo.2021.770400. eCollection 2021.
3
Toward the development of a vibrant, super-aged society: The future of medicine and society in Japan.迈向充满活力的超老龄社会:日本的医学与社会的未来。
Geriatr Gerontol Int. 2021 Aug;21(8):601-613. doi: 10.1111/ggi.14201. Epub 2021 Jul 1.
4
The type 2 diabetes-specific dementia risk score (DSDRS) is associated with frailty, cognitive and functional status amongst Mexican community-dwelling older adults.2 型糖尿病特异性痴呆风险评分(DSDRS)与墨西哥社区居住的老年成年人的虚弱、认知和功能状态相关。
BMC Geriatr. 2020 Sep 22;20(1):363. doi: 10.1186/s12877-020-01776-5.
5
Intensive glycemic control and macrovascular, microvascular, hypoglycemia complications and mortality in older (age ≥60years) or frail adults with type 2 diabetes: a systematic review and meta-analysis from randomized controlled trial and observation studies.强化血糖控制与老年(年龄≥60 岁)或虚弱的 2 型糖尿病成人的大血管、微血管、低血糖并发症和死亡率:来自随机对照试验和观察研究的系统评价和荟萃分析。
Expert Rev Endocrinol Metab. 2022 May;17(3):255-267. doi: 10.1080/17446651.2022.2079495. Epub 2022 May 25.
6
Effect of diabetes duration on the relationship between glycaemic control and risk of death in older adults with type 2 diabetes.糖尿病病程对老年 2 型糖尿病患者血糖控制与死亡风险关系的影响。
Diabetes Obes Metab. 2020 Feb;22(2):231-242. doi: 10.1111/dom.13891. Epub 2019 Nov 18.
7
Managing with Learning Disability and Diabetes: OK-Diabetes - a case-finding study and feasibility randomised controlled trial.管理学习障碍和糖尿病:OK-Diabetes-一项病例发现研究和可行性随机对照试验。
Health Technol Assess. 2018 May;22(26):1-328. doi: 10.3310/hta22260.
8
Protein intake is not associated with functional biomarkers of physical frailty: A cross-sectional analysis of community-dwelling older adults with type 2 diabetes mellitus.蛋白质摄入量与 2 型糖尿病社区居住的老年体弱患者的身体衰弱功能生物标志物无关:一项横断面分析。
Nutr Metab Cardiovasc Dis. 2021 Mar 10;31(3):827-833. doi: 10.1016/j.numecd.2020.11.018. Epub 2020 Nov 25.
9
Type 2 diabetes mellitus in older adults: clinical considerations and management.老年人 2 型糖尿病:临床注意事项与管理。
Nat Rev Endocrinol. 2021 Sep;17(9):534-548. doi: 10.1038/s41574-021-00512-2. Epub 2021 Jun 25.
10
Mean HbA, HbA variability, and mortality in people with diabetes aged 70 years and older: a retrospective cohort study.70 岁及以上糖尿病患者的平均 HbA、HbA 变异性和死亡率:一项回顾性队列研究。
Lancet Diabetes Endocrinol. 2018 Jun;6(6):476-486. doi: 10.1016/S2213-8587(18)30048-2. Epub 2018 Apr 16.

引用本文的文献

1
Noninvasive On-Skin Biosensors for Monitoring Diabetes Mellitus.用于监测糖尿病的无创皮肤生物传感器
Nanomicro Lett. 2025 Jul 31;18(1):16. doi: 10.1007/s40820-025-01843-9.
2
Frailty-stratified effectiveness of SGLT2 inhibitors versus DPP-4 inhibitors and GLP-1 receptor agonists on pulmonary outcomes in type 2 diabetes: a nationwide cohort study.钠-葡萄糖协同转运蛋白2抑制剂与二肽基肽酶-4抑制剂及胰高血糖素样肽-1受体激动剂相比,在2型糖尿病患者中基于衰弱分层的肺部结局疗效:一项全国性队列研究
EClinicalMedicine. 2025 Jul 3;85:103332. doi: 10.1016/j.eclinm.2025.103332. eCollection 2025 Jul.
3
Association of frailty and its trajectory with the risk of cancer: evidence from the China health and retirement longitudinal study (CHARLS).
衰弱及其轨迹与癌症风险的关联:来自中国健康与养老追踪调查(CHARLS)的证据。
BMC Public Health. 2025 May 15;25(1):1797. doi: 10.1186/s12889-025-22959-y.
4
Quality indicators for improved cardiovascular care: learnings from the National Institute for Health and Care Excellence.改善心血管护理的质量指标:来自英国国家卫生与临床优化研究所的经验教训。
Eur Heart J Qual Care Clin Outcomes. 2025 Jun 23;11(4):489-492. doi: 10.1093/ehjqcco/qcae097.
5
The Intersection between Frailty, Diabetes, and Hypertension: The Critical Role of Community Geriatricians and Pharmacists in Deprescribing.衰弱、糖尿病和高血压之间的交集:社区老年病医生和药剂师在减药中的关键作用。
J Pers Med. 2024 Aug 30;14(9):924. doi: 10.3390/jpm14090924.
6
Nutritional Interventions in Older Persons with Type 2 Diabetes and Frailty: A Scoping Systematic Review.2型糖尿病合并衰弱老年人的营养干预:一项范围界定性系统评价
J Cardiovasc Dev Dis. 2024 Sep 18;11(9):289. doi: 10.3390/jcdd11090289.
7
Frailty Detection in Older Adults with Diabetes: A Scoping Review of Assessment Tools and Their Link to Key Clinical Outcomes.糖尿病老年人的衰弱检测:评估工具及其与关键临床结局关联的范围综述
J Clin Med. 2024 Sep 9;13(17):5325. doi: 10.3390/jcm13175325.
8
Holistic and Personalized Strategies for Managing in Elderly Type 2 Diabetes Patients.综合与个体化策略在老年 2 型糖尿病患者管理中的应用。
Diabetes Metab J. 2024 Jul;48(4):531-545. doi: 10.4093/dmj.2024.0310. Epub 2024 Jul 26.
9
Diabetes in residential aged care: Pharmacological management and concordance with clinical guidelines.老年护理机构中的糖尿病:药物治疗及与临床指南的一致性
Australas J Ageing. 2024 Dec;43(4):792-801. doi: 10.1111/ajag.13351. Epub 2024 Jul 3.
10
Effects of comprehensive exercise training on frailty, negative emotions and physical functions of elderly patients with diabetes.综合运动训练对老年糖尿病患者衰弱、负面情绪及身体功能的影响
Pak J Med Sci. 2024 Jul;40(6):1225-1230. doi: 10.12669/pjms.40.6.7955.