1 Federal University of Goias (UFG), Goiânia, GO, Brazil.
2 Centro Brasileiro de Radioterapia, Oncologia e Mastologia (CEBROM), Goiânia, GO, Brazil.
Integr Cancer Ther. 2018 Sep;17(3):628-635. doi: 10.1177/1534735418757349. Epub 2018 Apr 10.
To investigate the influence of music therapy on the reduction of fatigue in women with breast or gynecological malignant neoplasia during radiotherapy, since it is one of the most frequent side effects of this type of treatment, and may interfere with self-esteem, social activities, and quality of life.
Randomized controlled trial (control group [CG] and music therapy group [MTG]) to assess fatigue, quality of life, and symptoms of depression in women undergoing radiotherapy using the Functional Assessment of Cancer Therapy: Fatigue (FACT-F) version 4, Functional Assessment of Cancer Therapy-General (FACT-G) version 4, and Beck Depression Inventory in 3 separate times, namely, during the first week of radiotherapy, on the week of the intermediary phase, and during the last week of radiotherapy. Individual 30- to 40-minute sessions of music therapy with the presence of a trained music therapist were offered to participants.
In this study, 164 women were randomized and 116 (63 CG and 53 MTG) were included in the analyses, with mean age of 52.90 years (CG) and 51.85 years (MTG). Participants in the MTG had an average of 10 music therapy sessions, totaling 509 sessions throughout the study. FACT-F results were significant regarding Trial Outcome Index ( P = .011), FACT-G ( P = .005), and FACT-F ( P = .001) for the MTG compared with the CG.
Individual music therapy sessions may be effective to reduce fatigue related to cancer and symptoms of depression, as well as to improve quality of life for women with breast or gynecological cancer undergoing radiotherapy. Further well-designed research studies are needed to adequately determine the effects of music therapy on fatigue.
研究音乐疗法对接受放疗的女性乳腺癌或妇科恶性肿瘤患者疲劳减轻的影响，因为疲劳是这种治疗方式最常见的副作用之一，可能会影响自尊心、社交活动和生活质量。
采用随机对照试验（对照组[CG]和音乐治疗组[MTG]），在放疗期间使用癌症治疗功能评估-疲劳量表（FACT-F）第 4 版、癌症治疗功能评估-一般量表（FACT-G）第 4 版和贝克抑郁量表（BDI）评估女性疲劳、生活质量和抑郁症状，共分 3 个时间点进行评估，即放疗第 1 周、中间阶段的第 1 周和放疗最后 1 周。为参与者提供每次 30-40 分钟的个体音乐治疗，由经过培训的音乐治疗师参与。
本研究共纳入 164 名女性，随机分为两组，116 名（63 名 CG 和 53 名 MTG）纳入分析，平均年龄分别为 52.90 岁（CG）和 51.85 岁（MTG）。MTG 组参与者平均接受了 10 次音乐治疗，整个研究共进行了 509 次治疗。MTG 组在试验结局指数（P =.011）、FACT-G（P =.005）和 FACT-F（P =.001）方面的 FACT-F 结果显著优于 CG 组。
对于接受放疗的乳腺癌或妇科癌症女性，个体音乐治疗可能有效减轻与癌症相关的疲劳和抑郁症状，并改善生活质量。需要进一步设计良好的研究来充分确定音乐疗法对疲劳的影响。
